2-Allylphenol

2-Allylphenol

SCHEMBL325760

C=CCc1ccccc1O.O=S(=O)(O)O

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of 2-Allylphenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.54
GABRA1 P14867 3/20 0.48
GABRB2 P47870 3/20 0.48
AKR1B1 P15121 2/20 0.45
HSPA5 P11021 1/20 0.45
MGLL Q99685 1/20 0.41
CYP2D6 P10635 1/20 0.41
TSHR P16473 1/20 0.41
HIF1A Q16665 1/20 0.41
CA12 O43570 4/20 0.40
CA2 P00918 4/20 0.40
CA9 Q16790 4/20 0.40
TAAR1 Q96RJ0 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CA1 P00915 1/20 0.39
ALOX5 P09917 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
GABRB1 P18505 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Allylphenol SCHEMBL17304231 0.98 POLB (0.53) POLBGABRA1GABRB2AKR1B1HSPA5
2-Allylphenol SCHEMBL27738263 0.98 POLB (0.53) POLBGABRA1GABRB2AKR1B1HSPA5
2-Allylphenol SCHEMBL17304230 0.98 POLB (0.53) POLBGABRA1GABRB2AKR1B1HSPA5
2-Allylphenol SCHEMBL4936146 0.93 POLB (0.49) POLBGABRA1GABRB2AKR1B1HSPA5
2-Allylphenol SCHEMBL28187371 0.93 POLB (0.51) POLBGABRA1GABRB2AKR1B1HSPA5
2-Allylphenol SCHEMBL28357989 0.92 POLB (0.47) POLBGABRA1GABRB2AKR1B1HSPA5
2-Allylphenol SCHEMBL11073238 0.92 POLB (0.47) POLBGABRA1GABRB2AKR1B1HSPA5
2-Allylphenol SCHEMBL28042926 0.91 POLB (0.53) POLBGABRA1GABRB2AKR1B1HSPA5
2-Allylphenol SCHEMBL27542206 0.90 POLB (0.46) POLBGABRA1GABRB2AKR1B1HSPA5
2-Allylphenol SCHEMBL88373 0.90 GABRA1 (0.53) POLBGABRA1GABRB2AKR1B1HSPA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2102 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114808048-B Electroless nickel plating solution and plating process thereof 上海亿尚金属有限公司 2024-04-30 CN claimed
CN-117624485-A Microgel acrylic emulsion and preparation method and application thereof 广东恒和永盛集团有限公司 2024-03-01 CN claimed
US-20240043771-A1 SOLID DETERGENT COMPOSITIONS AND METHODS OF ADJUSTING THE DISPENSE RATE OF SOLID DETERGENTS USING SOLID ANIONIC SURFACTANTS ECOLAB USA INC. 2024-02-08 US claimed
CN-113631682-B Polymer dispersions for wax inhibition during stimulation 能源解决方案(美国)有限责任公司 2024-01-26 CN claimed
US-20240026247-A1 PRESSED MANUAL DISH DETERGENT ECOLAB USA INC. 2024-01-25 US claimed
US-11820962-B2 Solid detergent compositions and methods of adjusting the dispense rate of solid detergents using solid anionic surfactants ECOLAB USA INC. (US) 2023-11-21 US claimed
CN-117069886-A Biological enzyme catalyzed aqueous acrylic ester emulsion and preparation method thereof 无锡海特新材料研究院有限公司 2023-11-17 CN claimed
US-11807759-B2 Emulsion compositions for priming a pavement surface ECOLAB USA INC. (US) 2023-11-07 US claimed
US-11746304-B2 Pressed manual dish detergent ECOLAB USA INC. (US) 2023-09-05 US claimed
CN-115819642-A Allyl ether sulfate polymerizable surfactants and methods of use 罗地亚经营管理公司 2023-03-21 CN claimed
EP-0197714-A2 Method for the control of dust CALGON CORPORATION (US) 1986-10-15 EP claimed
EP-0195638-A2 Method and compositions for the control of dust CALGON CORPORATION (US) 1986-09-24 EP claimed
EP-0194355-A1 Aqueous printing ink Union Camp Corporation (US) 1986-09-17 EP claimed
EP-0151884-A2 Liquid detergent compositions Albright & Wilson Limited (GB) 1985-08-21 EP claimed
EP-0124596-A4 CHEMICAL STERILIZATION OF IMPLANTABLE BIOLOGICAL TISSUE. AMERICAN HOSPITAL SUPPLY CORP (US) 1985-06-26 EP claimed
EP-0124596-A1 CHEMICAL STERILIZATION OF IMPLANTABLE BIOLOGICAL TISSUE BAXTER TRAVENOL LABORATORIES, INC. (US) 1984-11-14 EP claimed
WO-1984001894-A1 CHEMICAL STERILIZATION OF IMPLANTABLE BIOLOGICAL TISSUE AMERICAN HOSPITAL SUPPLY CORP (US) 1984-05-24 WO claimed
US-4148736-A THIXOTROPIC MIXTURE OF WATER, CHLOROFORM, ANIONIC AND CATIONIC SURFACTANTS, AN ACID, AND A BUFFER PHILLIPS PETROLEUM COMPANY (US) 1979-04-10 US claimed
US-4083604-A Thermomechanical fracture for recovery system in oil shale deposits TRW INC. (US) 1978-04-11 US claimed
US-4059308-A Pressure swing recovery system for oil shale deposits TRW INC. (US) 1977-11-22 US claimed