Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2179504 | 0.87 | RAB9A (0.45) | PDPK1MMP2MMP9MMP8MMP13 | |
| SCHEMBL2181427 | 0.77 | MEN1 (0.48) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL2179507 | 0.75 | PDPK1 (0.44) | PDPK1MMP2MMP9MMP8MMP13 | |
| SCHEMBL7950439 | 0.74 | MEN1 (0.52) | BACE1NPC1RAB9AMAPTPOLB | |
| SCHEMBL15241644 | 0.74 | NPC1 (0.62) | PDPK1MMP2MMP9MMP8MMP13 | |
| SCHEMBL2181392 | 0.72 | RAB9A (0.58) | PDPK1MMP2MMP9MMP8MMP13 | |
| SCHEMBL3251954 | 0.72 | MTOR (0.48) | PDPK1MMP2MMP9MMP8MMP13 | |
| SCHEMBL12414216 | 0.66 | FOXO1 (0.61) | MMP2MMP9MMP8MMP13COMT | |
| SCHEMBL12830503 | 0.66 | MEN1 (0.42) | NPC1RAB9AMAPTKDM4EPOLB | |
| SCHEMBL12434682 | 0.66 | NPC1 (0.57) | PDPK1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025295-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-04 | — | — | WO | disclosed |