Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 6/20 | 0.70 |
| ▸ | TYR | P14679 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ELANE | P08246 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9625602 | 0.87 | DAO (0.66) | DAOTYRKDM4EELANE | |
| Kojic Acid SCHEMBL3262759 | 0.86 | TYR (0.76) | DAOTYRKDM4EELANE | |
| SCHEMBL9625178 | 0.84 | DAO (0.62) | DAOTYRKDM4EELANE | |
| SCHEMBL14129749 | 0.83 | DAO (0.76) | DAOTYRKDM4EELANE | |
| SCHEMBL3212791 | 0.82 | DAO (1.00) | DAOTYRKDM4EELANE | |
| SCHEMBL10494163 | 0.82 | ELANE (0.66) | DAOTYRKDM4EELANE | |
| SCHEMBL10494181 | 0.82 | ELANE (0.66) | DAOTYRKDM4EELANE | |
| SCHEMBL10494142 | 0.82 | ELANE (0.66) | DAOTYRKDM4EELANE | |
| SCHEMBL902947 | 0.80 | TYR (0.70) | DAOTYRKDM4E | |
| Kojic Acid SCHEMBL27429993 | 0.78 | TYR (0.88) | DAOTYRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102661-A | Nontoxic; cosmetics for skin disorder | SANSHO SEIYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | claimed |
| EP-0473764-A1 | METAL COMPLEXES | Hider, Robert Charles (GB) | 1992-03-11 | — | — | EP | claimed |
| WO-1991014664-A1 | METAL COMPLEXES | HIDER ROBERT CHARLES (GB) | 1991-10-03 | — | — | WO | claimed |
| EP-0417632-A2 | 2-Ethoxymethyl-5-hydroxy-gamma-pyrone and melanogenesis-inhibiting endermic preparation containing the same compound as active ingredient | Sansho Seiyaku Co., Ltd. (JP) | 1991-03-20 | — | — | EP | claimed |
| US-20160074315-A1 | TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF | STIEFEL LABORATORIES, INC. | 2016-03-17 | — | — | US | disclosed |
| EP-2219600-A1 | TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF | STIEFEL LABORATORIES, INC. (US) | 2010-08-25 | — | — | EP | disclosed |
| US-20100034757-A1 | EXTRACT POWDER OF INDIGO PLANT, AND ITS PREPARATION AND USES | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2010-02-11 | — | — | US | disclosed |
| US-20090263339-A1 | AGENT FOR EXTERNAL APPLICATION TO THE SKIN | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKY (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-2087903-A1 | EXTRACT POWDER OF INDIGO-CONTAINING PLANT, METHOD FOR PRODUCTION THEREOF, AND USE THEREOF | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2009-08-12 | — | — | EP | disclosed |
| WO-2009067095-A1 | TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF | STIEFEL LABORATORIES, INC. (US) | 2009-05-28 | — | — | WO | disclosed |
| EP-1602354-B1 | Use of polyglutamic acid or its salts | MEIJI SEIKA KAISHA (JP) | 2008-11-05 | — | — | EP | disclosed |
| EP-1604647-B1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | CHISSO CORP (JP) | 2008-05-07 | — | — | EP | disclosed |
| WO-2003057184-A2 | HYDROXAMIC ACID AND ITS DERIVATIVES AS INHIBITORS OF MELANOCYTE TYROSINASE FOR TOPICAL SKIN LIGHTENERS | INTEGRIDERM, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-5102661-A | Nontoxic; cosmetics for skin disorder | SANSHO SEIYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| US-5102661-A | Nontoxic; cosmetics for skin disorder | SANSHO SEIYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0473764-A1 | METAL COMPLEXES | Hider, Robert Charles (GB) | 1992-03-11 | — | — | EP | disclosed |
| WO-1991014664-A1 | METAL COMPLEXES | HIDER ROBERT CHARLES (GB) | 1991-10-03 | — | — | WO | disclosed |
| EP-0417632-A2 | 2-Ethoxymethyl-5-hydroxy-gamma-pyrone and melanogenesis-inhibiting endermic preparation containing the same compound as active ingredient | Sansho Seiyaku Co., Ltd. (JP) | 1991-03-20 | — | — | EP | disclosed |
| EP-0417632-A2 | 2-Ethoxymethyl-5-hydroxy-gamma-pyrone and melanogenesis-inhibiting endermic preparation containing the same compound as active ingredient | Sansho Seiyaku Co., Ltd. (JP) | 1991-03-20 | — | — | EP | disclosed |
| EP-0417632-A2 | 2-Ethoxymethyl-5-hydroxy-gamma-pyrone and melanogenesis-inhibiting endermic preparation containing the same compound as active ingredient | Sansho Seiyaku Co., Ltd. (JP) | 1991-03-20 | — | — | EP | disclosed |