Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 6/20 | 0.62 |
| ▸ | ELANE | P08246 | 2/20 | 0.61 |
| ▸ | TYR | P14679 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494142 | 0.94 | ELANE (0.66) | DAOELANETYRKDM4E | |
| SCHEMBL10494163 | 0.94 | ELANE (0.66) | DAOELANETYRKDM4E | |
| SCHEMBL10494181 | 0.94 | ELANE (0.66) | DAOELANETYRKDM4E | |
| SCHEMBL9625602 | 0.91 | DAO (0.66) | DAOELANETYRKDM4E | |
| SCHEMBL3258342 | 0.84 | DAO (0.70) | DAOELANETYRKDM4E | |
| SCHEMBL14129749 | 0.78 | DAO (0.76) | DAOELANETYRKDM4E | |
| SCHEMBL3212791 | 0.77 | DAO (1.00) | DAOELANETYRKDM4E | |
| SCHEMBL30982893 | 0.76 | TYR (0.64) | DAOELANETYRKDM4E | |
| SCHEMBL11036240 | 0.75 | ELANE (0.48) | DAOELANETYR | |
| SCHEMBL902947 | 0.75 | TYR (0.70) | DAOTYRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473764-A1 | METAL COMPLEXES | Hider, Robert Charles (GB) | 1992-03-11 | — | — | EP | claimed |
| WO-1991014664-A1 | METAL COMPLEXES | HIDER ROBERT CHARLES (GB) | 1991-10-03 | — | — | WO | claimed |
| US-9346799-B2 | Useful combinations of monobactam antibiotics with beta-lactamase inhibitors | BASILEA PHARMACEUTICALS AG (CH) | 2016-05-24 | — | — | US | disclosed |
| US-20160122320-A1 | USEFUL COMBINATIONS OF MONOBACTAM ANTIBIOTICS WITH BETA-LACTAMASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2016-05-05 | — | — | US | disclosed |
| US-20150031662-A1 | USEFUL COMBINATIONS OF MONOBACTAM ANTIBIOTICS WITH BETA-LACTAMASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2015-01-29 | — | — | US | disclosed |
| US-8901293-B2 | Useful combinations of monobactam antibiotics with beta-lactamase inhibitors | BASILEA PHARMACEUTICA AG (CH) | 2014-12-02 | — | — | US | disclosed |
| EP-2484680-A1 | Useful Combinations of Monobactam Antibiotics with beta-Lac-tamase Inhibitors | Basilea Pharmaceutica AG (CH) | 2012-08-08 | — | — | EP | disclosed |
| EP-2308874-A1 | Useful beta-lactamase inhibitors | Basilea Pharmaceutica AG (CH) | 2011-04-13 | — | — | EP | disclosed |
| US-20100056478-A1 | Useful Combinations of Monobactam Antibiotics With Beta-Lactamase Inhibitors | BASILEA PHARMACEUTICA AG (CH) | 2010-03-04 | — | — | US | disclosed |
| WO-2007065288-A2 | USEFUL COMBINATIONS OF MONOBACTAM ANTIBIOTICS WITH BETA-LACTAMASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2007-06-14 | — | — | WO | disclosed |
| EP-0473764-A1 | METAL COMPLEXES | Hider, Robert Charles (GB) | 1992-03-11 | — | — | EP | disclosed |
| WO-1991014664-A1 | METAL COMPLEXES | HIDER ROBERT CHARLES (GB) | 1991-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031662-A1 | USEFUL COMBINATIONS OF MONOBACTAM ANTIBIOTICS WITH BETA-LACTAMASE INHIBITORS | MGAM, MGAM2, B2M | DAO 662/4885ELANE 143/4885TYR 4442/4885 |
| US-20160122320-A1 | USEFUL COMBINATIONS OF MONOBACTAM ANTIBIOTICS WITH BETA-LACTAMASE INHIBITORS | MGAM, MGAM2, B2M | DAO 662/4885ELANE 143/4885TYR 4442/4885 |
| US-20100056478-A1 | Useful Combinations of Monobactam Antibiotics With Beta-Lactamase Inhibitors | MGAM, MGAM2, B2M | DAO 506/4885ELANE 133/4885TYR 4381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.