Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30599264 | 1.00 | HPGD (0.64) | HPGDALDH1A1SMN1; SMN2LMNAMAPT | |
| Hydrochloric Acid SCHEMBL5168951 | 0.99 | HPGD (0.62) | HPGDALDH1A1SMN1; SMN2LMNAMAPT | |
| Oxalic Acid SCHEMBL5167729 | 0.94 | HPGD (0.57) | HPGDALDH1A1SMN1; SMN2LMNAMAPT | |
| Fumaric Acid SCHEMBL5168906 | 0.92 | HPGD (0.54) | HPGDALDH1A1SMN1; SMN2LMNAMAPT | |
| Trifluoroacetic Acid SCHEMBL5180863 | 0.89 | HPGD (0.52) | HPGDALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL7905734 | 0.83 | PPARG (0.54) | HPGDALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL7905732 | 0.83 | PPARG (0.54) | HPGDALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL5167466 | 0.83 | KDM4E (0.49) | HPGDALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL18015059 | 0.82 | PPARG (0.57) | HPGDALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL10699030 | 0.82 | PPARG (0.57) | ALDH1A1SMN1; SMN2PPARGCYP3A4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496207-A | Method for green synthesis of 4- [2- (5-ethyl-2-pyridyl) ethoxy ] benzaldehyde | 上海北卡医药技术有限公司 | 2023-07-28 | — | — | CN | claimed |
| CN-108484488-B | Method for synthesizing 4- [2- (5-ethyl-2-pyridyl) ethoxy ] benzaldehyde by photo/nickel concerted catalysis | 陕西师范大学 | 2021-06-08 | — | — | CN | claimed |
| CN-106279144-B | Method for preparing pioglitazone impurity C by one-pot method | 浙江华海药业股份有限公司 | 2020-07-17 | — | — | CN | claimed |
| US-20090118514-A1 | PROCESSES FOR PREPARING PIOGLITAZONE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | DR. REDDY'S LABORATORIES, INC. | 2009-05-07 | — | — | US | claimed |
| WO-2008075380-A2 | PROCESS FOR THE PREPARATION OF THIAZOLIDINE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-06-26 | — | — | WO | claimed |
| EP-1694646-B1 | PROCESS FOR THE SYNTHESIS OF PIOGLITAZONE HYDROGEN CHLORIDE | RICHTER GEDEON VEGYESZET (HU) | 2007-04-25 | — | — | EP | claimed |
| EP-1694646-A1 | PROCESS FOR THE SYNTHESIS OF PIOGLITAZONE HYDROGEN CHLORIDE | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2006-08-30 | — | — | EP | claimed |
| WO-2005058827-A1 | PROCESS FOR THE SYNTHESIS OF PIOGLITAZONE HYDROGEN CHLORIDE | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2005-06-30 | — | — | WO | claimed |
| JP-9118678-A | — | — | None | — | — | JP | disclosed |
| JP-5112483-A | — | — | None | — | — | JP | disclosed |
| JP-10072438-A | — | — | None | — | — | JP | disclosed |
| CN-116496207-A | Method for green synthesis of 4- [2- (5-ethyl-2-pyridyl) ethoxy ] benzaldehyde | 上海北卡医药技术有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-116496207-A | Method for green synthesis of 4- [2- (5-ethyl-2-pyridyl) ethoxy ] benzaldehyde | 上海北卡医药技术有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-116496207-A | Method for green synthesis of 4- [2- (5-ethyl-2-pyridyl) ethoxy ] benzaldehyde | 上海北卡医药技术有限公司 | 2023-07-28 | — | — | CN | disclosed |
| JP-H05112483-A | PRODUCTION OF ETHER COMPOUND | TAKEDA CHEM IND LTD | 1993-05-07 | — | — | JP | disclosed |
| EP-0506273-A2 | Method for producing ethers | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-30 | — | — | EP | disclosed |
| EP-0257781-B1 | A METHOD FOR PRODUCING THIAZOLIDINEDIONE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-4898947-A | Pyridine and thiazolidinedione derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| US-4812570-A | Method for producing thiazolidinedione derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-03-14 | — | — | US | disclosed |
| EP-0257781-A1 | A method for producing thiazolidinedione derivatives | Takeda Chemical Industries, Ltd. (JP) | 1988-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118514-A1 | PROCESSES FOR PREPARING PIOGLITAZONE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | DPP4, SLC5A2, SLC5A1 | HPGD 291/4885ALDH1A1 3140/4885SMN1; SMN2 1389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.