Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3258559 | 0.83 | HPGD (0.64) | KDM4EALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL30599264 | 0.83 | HPGD (0.64) | KDM4EALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL20333180 | 0.82 | TYR (0.47) | KDM4EALDH1A1SMN1; SMN2HPGDMAPT | |
| Hydrochloric Acid SCHEMBL5168951 | 0.82 | HPGD (0.62) | KDM4EALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL10504713 | 0.80 | SMN1; SMN2 (0.52) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL2231854 | 0.78 | ALDH1A1 (0.61) | KDM4EALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL2232274 | 0.78 | ALDH1A1 (0.61) | KDM4EALDH1A1SMN1; SMN2HPGDMAPT | |
| Oxalic Acid SCHEMBL5167729 | 0.78 | HPGD (0.57) | ALDH1A1SMN1; SMN2HPGDMAPTLMNA | |
| SCHEMBL8390283 | 0.77 | ALDH1A1 (0.69) | KDM4EALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL10504130 | 0.77 | MEN1 (0.50) | ALDH1A1SMN1; SMN2MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694646-B1 | PROCESS FOR THE SYNTHESIS OF PIOGLITAZONE HYDROGEN CHLORIDE | RICHTER GEDEON VEGYESZET (HU) | 2007-04-25 | — | — | EP | disclosed |
| EP-1694646-A1 | PROCESS FOR THE SYNTHESIS OF PIOGLITAZONE HYDROGEN CHLORIDE | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005058827-A1 | PROCESS FOR THE SYNTHESIS OF PIOGLITAZONE HYDROGEN CHLORIDE | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2005-06-30 | — | — | WO | disclosed |