Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 12/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 12/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 12/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1918512 | 0.94 | — | — | |
| SCHEMBL23785996 | 0.94 | — | — | |
| SCHEMBL5739697 | 0.88 | CHRM2 (0.49) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL15971525 | 0.81 | — | — | |
| SCHEMBL14878574 | 0.74 | POLB (0.41) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL19408961 | 0.74 | — | — | |
| SCHEMBL30489287 | 0.74 | — | — | |
| SCHEMBL3488662 | 0.74 | — | — | |
| SCHEMBL21773024 | 0.74 | — | — | |
| SCHEMBL18629522 | 0.72 | POLB (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786312-B2 | Methods of preparing heterocyclic boronic acids and derivatives thereof | PHENOMIX CORPORATION (US) | 2010-08-31 | — | — | US | disclosed |
| US-20080300413-A1 | Methods of Preparing Hetercyclic Boronic Acids and Derivatives Thereof | SINO-MED INTERNATIONAL ALLIANCE, INC. | 2008-12-04 | — | — | US | disclosed |
| EP-1919485-A1 | METHODS OF PREPARING HETERCYCLIC BORONIC ACIDS AND DERIVATIVES THEREOF | Phenomix Corporation (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007016356-A1 | METHODS OF PREPARING HETERCYCLIC BORONIC ACIDS AND DERIVATIVES THEREOF | PHENOMIX CORPORATION (US) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300413-A1 | Methods of Preparing Hetercyclic Boronic Acids and Derivatives Thereof | HLCS, NISCH, BTD | CHRM2 2680/4885CHRM4 1759/4885CHRM5 2108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.