Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 14/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 14/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 14/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 14/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 14/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23785996 | 0.93 | — | — | |
| SCHEMBL1918512 | 0.93 | — | — | |
| SCHEMBL3259043 | 0.88 | CHRM2 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL15971525 | 0.84 | — | — | |
| SCHEMBL385022 | 0.80 | GAA (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4002060 | 0.80 | GAA (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4179330 | 0.80 | GAA (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL30443171 | 0.78 | CHRM2 (0.37) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4282472 | 0.78 | TSHR (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6694119 | 0.78 | DPP4 (0.40) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106661047-A | Benzothiadiazoles amines | 拜耳制药股份公司 | 2017-05-10 | — | — | CN | claimed |
| CN-106661047-A | Benzothiadiazoles amines | 拜耳制药股份公司 | 2017-05-10 | — | — | CN | disclosed |
| EP-1615904-A2 | SUBSTITUTED BENZOSULPHONAMIDE AS POTENTIATORS OF GLUTAMATE RECEPTORS | AstraZeneca AB (SE) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004092135-A2 | SUBSTITUTED BENZOSULPHONAMIDE AS POTENTIATORS OF GLUTAMATE RECEPTORS | ASTRAZENECA (SE) | 2004-10-28 | — | — | WO | disclosed |