Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PNP | P00491 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | NT5E | P21589 | 2/20 | 0.50 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | HINT1 | P49773 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952851 | 1.00 | AHCY (0.58) | AHCYLMNAPNPTP53HTT | |
| SCHEMBL21562190 | 1.00 | AHCY (0.58) | AHCYLMNAPNPTP53HTT | |
| SCHEMBL14075790 | 0.88 | LMNA (0.49) | LMNAPNPTP53HTTPDE4D | |
| SCHEMBL19959557 | 0.88 | PDE4D (0.66) | LMNAPNPTP53HTTPDE4D | |
| SCHEMBL13224455 | 0.88 | LMNA (0.50) | AHCYLMNAPNPTP53HTT | |
| SCHEMBL3436979 | 0.88 | PDE4D (0.66) | LMNAPNPTP53HTTPDE4D | |
| SCHEMBL8287088 | 0.88 | ADORA3 (0.55) | LMNAPNPTP53HTTPDE4D | |
| SCHEMBL21132768 | 0.88 | LMNA (0.65) | AHCYLMNAPNPTP53HTT | |
| SCHEMBL3436977 | 0.88 | PDE4D (0.66) | LMNAPNPTP53HTTPDE4D | |
| SCHEMBL20419178 | 0.88 | LMNA (0.49) | LMNAPNPTP53HTTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7666851-B1 | Three ring fused analogs of isoguanosine | BENNER STEVEN ALBERT | 2010-02-23 | — | — | US | disclosed |