Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3259726 | 0.89 | LMNA (0.36) | LMNA | |
| SCHEMBL3050255 | 0.82 | LMNA (0.31) | LMNA | |
| SCHEMBL3786697 | 0.79 | — | — | |
| SCHEMBL622232 | 0.78 | CA2 (0.35) | — | |
| SCHEMBL3786684 | 0.71 | CYP2C19 (0.33) | LMNA | |
| SCHEMBL9000085 | 0.71 | CA2 (0.34) | — | |
| SCHEMBL10305674 | 0.71 | CYP2C19 (0.39) | LMNA | |
| SCHEMBL3041876 | 0.69 | LMNA (0.47) | LMNA | |
| SCHEMBL5685875 | 0.68 | CYP2C19 (0.54) | LMNA | |
| SCHEMBL9191001 | 0.67 | LMNA (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203189-B1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2012-07-18 | — | — | EP | claimed |
| US-20100221191-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2010-09-02 | — | — | US | claimed |
| EP-2203189-B1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2012-07-18 | — | — | EP | disclosed |
| US-20100221191-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100221191-A1 | CONTRAST AGENTS | C5, C1S, C1R | LMNA 1527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.