Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010132 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6 | |
| SCHEMBL5012382 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6 | |
| SCHEMBL5013845 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6 | |
| SCHEMBL1004096 | 0.98 | ALDH1A1 (0.46) | ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6 | |
| SCHEMBL29891613 | 0.98 | ALDH1A1 (0.46) | ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6 | |
| Anthraquinone SCHEMBL28175362 | 0.85 | CES1 (0.44) | ALDH1A1HSD17B10HIF1ACYP1B1CYP3A4 | |
| SCHEMBL17967022 | 0.83 | CYP1A2 (0.42) | ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6 | |
| SCHEMBL25966 | 0.78 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6 | |
| SCHEMBL190685 | 0.78 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6 | |
| SCHEMBL15063036 | 0.78 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112694388-A | Naphthacene derivative and preparation method and application thereof | 中国科学院化学研究所 | 2021-04-23 | — | — | CN | disclosed |
| US-7651746-B2 | Halogenated bisdiarylaminopolycyclic aromatic compounds and polymers thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-01-26 | — | — | US | disclosed |
| CN-100482634-C | Organic electroluminescent device | IDEMITSU PETROCHEMICAL CO (JP) | 2009-04-29 | — | — | CN | disclosed |
| US-20070126345-A1 | Halogenated bisdiarylaminopolycylic aromatic compounds and polymers thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | US | disclosed |
| CN-1721499-A | Organic electroluminescent device | IDEMITSU KOSAN CO (JP) | 2006-01-18 | — | — | CN | disclosed |
| CN-1219747-C | Organic electroluminescent device | IDEMITSU KOSAN CO (JP) | 2005-09-21 | — | — | CN | disclosed |
| WO-2005049546-A1 | HALOGENATED BISDIARYLAMINOPOLYCYLIC AROMATIC COMPOUNDS AND POLYMERS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-06-02 | — | — | WO | disclosed |
| CN-1292022-A | Organic electroluminescent device | IDEMITSU KOSAN CO (JP) | 2001-04-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070126345-A1 | Halogenated bisdiarylaminopolycylic aromatic compounds and polymers thereof | AHR, AADAC, ARNT | ALDH1A1 667/4885HSD17B10 951/4885HIF1A 3596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.