Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP8B1 | Q9UNU6 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3177584 | 0.84 | MAP4K4 (0.52) | CYP8B1PIK3CACYP2C19MAP4K4PIK3CD | |
| SCHEMBL3162840 | 0.78 | CYP8B1 (0.47) | CYP8B1PIK3CACYP2C19MAP4K4AAK1 | |
| SCHEMBL3259297 | 0.77 | CYP8B1 (0.45) | CYP8B1PIK3CACYP2C19MAP4K4PIK3CD | |
| SCHEMBL13527140 | 0.76 | CYP8B1 (0.48) | CYP8B1PIK3CACYP2C19MAP4K4AAK1 | |
| SCHEMBL5905803 | 0.76 | CYP8B1 (0.50) | CYP8B1PIK3CACYP2C19PIK3CDPIK3CB | |
| SCHEMBL3162808 | 0.76 | CYP8B1 (0.49) | CYP8B1PIK3CACYP2C19MAP4K4PIK3CD | |
| SCHEMBL3667650 | 0.76 | CYP8B1 (0.51) | CYP8B1PIK3CACYP2C19MAP4K4PIK3CD | |
| SCHEMBL3668757 | 0.76 | CYP8B1 (0.51) | CYP8B1PIK3CACYP2C19MAP4K4PIK3CD | |
| SCHEMBL3665597 | 0.76 | CYP8B1 (0.51) | CYP8B1PIK3CACYP2C19MAP4K4PIK3CD | |
| SCHEMBL10078646 | 0.74 | CYP8B1 (0.53) | CYP8B1PIK3CACYP2C19PIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7648984-B2 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2010-01-19 | — | — | US | disclosed |
| US-20070203127-A1 | Antibacterial Agents | GLAXO GROUP LIMITED (GB) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203127-A1 | Antibacterial Agents | NQO2, NQO1, NDUFV2 | CYP8B1 965/4885PIK3CA 3189/4885CYP2C19 2393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.