SCHEMBL3259359

SCHEMBL3259359

CCCc1cccc(OP(=O)(O)O)c1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 2/20 0.44
INPP5A Q14642 2/20 0.44
INPP5B P32019 1/20 0.44
KDM4E B2RXH2 1/20 0.43
USP2 O75604 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
PDE3A Q14432 1/20 0.43
HSD17B10 Q99714 1/20 0.43
SRC P12931 3/20 0.40
HTR2A P28223 3/20 0.39
HTR2C P28335 3/20 0.39
HTR2B P41595 3/20 0.39
HTR1A P08908 1/20 0.39
LTB4R Q15722 1/20 0.38
LTB4R2 Q9NPC1 1/20 0.38
PTPN5 P54829 1/20 0.36
PPARA Q07869 1/20 0.35
ELANE P08246 1/20 0.35
AKT1 P31749 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8079854 0.92 HTR2A (0.42) INPPL1INPP5AINPP5BKDM4EUSP2
SCHEMBL444782 0.83 KDM4E (0.38) INPPL1INPP5AINPP5BKDM4EUSP2
SCHEMBL1100623 0.83 INPPL1 (0.48) INPPL1INPP5AINPP5BKDM4EUSP2
SCHEMBL1191887 0.82 INPPL1 (0.42) INPPL1INPP5AINPP5BKDM4EUSP2
SCHEMBL11330673 0.81 KDM4E (0.38) INPPL1INPP5AINPP5BKDM4EUSP2
SCHEMBL1834263 0.79 LTB4R (0.41) KDM4EALDH1A1HPGDLTB4RLTB4R2
SCHEMBL5959297 0.79 INPPL1 (0.49) INPPL1INPP5AINPP5BKDM4EUSP2
SCHEMBL30523469 0.79 INPPL1 (0.49) INPPL1INPP5AINPP5BKDM4EUSP2
SCHEMBL9356944 0.79 INPPL1 (0.42) INPPL1INPP5AINPP5BKDM4EUSP2
Biphenyl SCHEMBL28005747 0.79 HSD17B10 (0.50) INPPL1INPP5AINPP5BKDM4EUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7527902-B2 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION (US) 2009-05-05 US claimed
US-20070026328-A1 Photoreceptor layer having phosphorus-containing lubricant XEROX CORPORATION 2007-02-01 US claimed
US-20070026330-A1 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION 2007-02-01 US claimed
US-7651827-B2 Photoreceptor layer having phosphorus-containing lubricant XEROX CORPORATION (US) 2010-01-26 US disclosed
US-7527902-B2 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION (US) 2009-05-05 US disclosed
US-20070026328-A1 Photoreceptor layer having phosphorus-containing lubricant XEROX CORPORATION 2007-02-01 US disclosed
US-20070026330-A1 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION 2007-02-01 US disclosed
US-6586376-B1 Sterically hindered polyol ester and polyphenyl thioether, oxidation resistance; jet turbine engines EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2003-07-01 US disclosed
US-6511947-B1 A mixture of a polyphenyl ether having 4-5 aromatic rings and/or its hydrocarbon substituted group with a polyphenyl thioether having 3-5 aromatic rings, an amine antioxidant, a phosphate, and an amine salt of acid phosphate TONEN GENERAL SEKIYU K.K. (JP) 2003-01-28 US disclosed
US-6191080-B1 MIXTURE OF POLYOL ESTERS, MIXTURE OF POLYPHENYLENE ETHER AND POLYOL ESTER AND POLYPHENYLENE THIOETHERS TONEN CORPORATION (JP) 2001-02-20 US disclosed
EP-0719853-B1 Fluid composition for use in fluid coupling TONEN CORP (JP) 2000-09-20 EP disclosed
EP-0636682-B1 Fluid composition for fluid coupling TONEN CORP (JP) 1999-09-22 EP disclosed
EP-0889112-A1 LUBRICATING OIL COMPOSITION FOR AUTOMATIC TRANSMISSIONS TONEN CORPORATION (JP) 1999-01-07 EP disclosed
US-5747429-A SILICONE OIL TONEN CORPORATION (JP) 1998-05-05 US disclosed
US-5656577-A CONSISTS OF POLYSILOXANE BASED OILS; THIADIAZOLE DERIVATIVES, AMINE ANTIOXIDANTS AND POSPHORIC OR THIOPHOSPHORIC AND OTHER PHOSPHORUS COMPOUNDS OR CARBAMATES AS WEAR PREVENTIVE; EXCELLENT VISCOSITY AND TORQUE STABILITY TONEN CORPORATION (JP) 1997-08-12 US disclosed
EP-0778334-A1 HEAT-RESISTANT LUBRICATING OIL COMPOSITION Tonen Corporation (JP) 1997-06-11 EP disclosed
EP-0719853-A2 Fluid composition for use in fluid coupling Tonen Corporation (JP) 1996-07-03 EP disclosed
EP-0636682-A1 Fluid composition for fluid coupling Tonen Corporation (JP) 1995-02-01 EP disclosed