SCHEMBL444782

SCHEMBL444782

CCCc1ccc(OP(=O)(O)O)c(-c2ccccc2)c1CCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 3/20 0.38
USP2 O75604 1/20 0.38
PDE3A Q14432 1/20 0.38
HSD17B10 Q99714 1/20 0.38
INPPL1 O15357 4/20 0.37
INPP5A Q14642 3/20 0.37
SRC P12931 2/20 0.37
AKT1 P31749 1/20 0.37
NCEH1 Q6PIU2 1/20 0.35
INPP5B P32019 1/20 0.35
GPR84 Q9NQS5 1/20 0.35
LTB4R Q15722 1/20 0.34
LTB4R2 Q9NPC1 1/20 0.34
GAA P10253 2/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL448371 0.90 GCGR (0.40) KDM4EALDH1A1HPGDUSP2PDE3A
SCHEMBL29493895 0.85 KDM4E (0.41) KDM4EALDH1A1HPGDUSP2PDE3A
SCHEMBL446046 0.85 KDM4E (0.41) KDM4EALDH1A1HPGDUSP2PDE3A
SCHEMBL3259359 0.83 INPPL1 (0.44) KDM4EALDH1A1HPGDUSP2PDE3A
SCHEMBL11330673 0.81 KDM4E (0.38) KDM4EALDH1A1HPGDUSP2PDE3A
SCHEMBL381550 0.81 INPPL1 (0.44) KDM4EALDH1A1HPGDUSP2PDE3A
SCHEMBL11805355 0.78 ALDH1A1 (0.40) KDM4EALDH1A1HPGDUSP2PDE3A
SCHEMBL5959297 0.77 INPPL1 (0.49) KDM4EALDH1A1HPGDUSP2PDE3A
SCHEMBL30523469 0.77 INPPL1 (0.49) KDM4EALDH1A1HPGDUSP2PDE3A
SCHEMBL5675233 0.76 GCGR (0.42) GPR84GCGRPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels ExxonMobil Technology and Engineering Company (US) 2026-04-28 US disclosed
US-12577493-B2 Bio-based lubricant compositions ExxonMobil Technology and Engineering Company (US) 2026-03-17 US disclosed
EP-4705417-A1 INTERNAL COMBUSTION ENGINE LUBRICANT ExxonMobil Technology and Engineering Company (US) 2026-03-11 EP disclosed
EP-4101919-B1 REFRIGERATOR OIL COMPOSITION AND REFRIGERATOR MIXTURE COMPOSITION IDEMITSU KOSAN CO (JP) 2025-09-17 EP disclosed
US-12384980-B2 Internal combustion engine lubricant ExxonMobil Technology and Engineering Company (US) 2025-08-12 US disclosed
US-20250215838-A1 ENGINE LUBRICANT OPTIMIZATION FOR ADVANCED SUSTAINABLE FUELS ExxonMobil Technology and Engineering Company (US) 2025-07-03 US disclosed
US-20240409840-A1 BIO-BASED LUBRICANT COMPOSITIONS ExxonMobil Technology and Engineering Company (US) 2024-12-12 US disclosed
WO-2024229029-A1 INTERNAL COMBUSTION ENGINE LUBRICANT ExxonMobil Technology and Engineering Company (US) 2024-11-07 WO disclosed
US-20240368493-A1 INTERNAL COMBUSTION ENGINE LUBRICANT ExxonMobil Technology and Engineering Company (US) 2024-11-07 US disclosed
US-11760952-B2 Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods INGEVITY SOUTH CAROLINA, LLC (US) 2023-09-19 US disclosed
EP-1008643-A2 Refrigerator oil composition, and method of using the composition for lubrication IDEMITSU KOSAN COMPANY LIMITED (JP) 2000-06-14 EP disclosed
US-5972854-A PREVENTS BRAKE LINING OF CLUTCH OF AUTOMATIC TRANSMISSIONS FROM SHUDDERING IDEMITSU KOSAN CO., LTD. (JP) 1999-10-26 US disclosed
EP-0636682-B1 Fluid composition for fluid coupling TONEN CORP (JP) 1999-09-22 EP disclosed
EP-0812900-A2 Lubricating oil composition for automatic transmission IDEMITSU KOSAN COMPANY LIMITED (JP) 1997-12-17 EP disclosed
US-5656577-A CONSISTS OF POLYSILOXANE BASED OILS; THIADIAZOLE DERIVATIVES, AMINE ANTIOXIDANTS AND POSPHORIC OR THIOPHOSPHORIC AND OTHER PHOSPHORUS COMPOUNDS OR CARBAMATES AS WEAR PREVENTIVE; EXCELLENT VISCOSITY AND TORQUE STABILITY TONEN CORPORATION (JP) 1997-08-12 US disclosed
EP-0748863-A2 Traction drive fluid composition COSMO RESEARCH INSTITUTE (JP) 1996-12-18 EP disclosed
EP-0397507-B1 Silicone fluids for viscous couplings TONEN CORP (JP) 1995-03-15 EP disclosed
EP-0636682-A1 Fluid composition for fluid coupling Tonen Corporation (JP) 1995-02-01 EP disclosed
US-5332515-A Polysiloxane, phosphorus type anti-wear agent TONEN CORPORATION (JP) 1994-07-26 US disclosed
EP-0397507-A1 Silicone fluids for viscous couplings Tonen Corporation (JP) 1990-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577493-B2 Bio-based lubricant compositions DEGS1, DSG1, DEK KDM4E 4561/4885ALDH1A1 1312/4885HPGD 2078/4885
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels TST, TCF4, MLLT1 KDM4E 55/4885ALDH1A1 1805/4885HPGD 3859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.