Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL326893 | 0.80 | MCHR1 (0.63) | MCHR1KCNH2 | |
| SCHEMBL322400 | 0.80 | UTS2R (0.47) | MCHR1KCNH2UTS2RCD274FAAH | |
| SCHEMBL320844 | 0.78 | MCHR1 (0.75) | MCHR1KCNH2 | |
| SCHEMBL326280 | 0.78 | MCHR1 (0.41) | MCHR1KCNH2UTS2R | |
| SCHEMBL10190043 | 0.74 | UTS2R (0.44) | MCHR1KCNH2UTS2R | |
| SCHEMBL10263931 | 0.72 | MCHR1 (0.64) | MCHR1KCNH2 | |
| SCHEMBL16161556 | 0.72 | KCNH2 (0.46) | MCHR1KCNH2UTS2RCD274 | |
| SCHEMBL321107 | 0.71 | MCHR1 (0.65) | MCHR1KCNH2 | |
| SCHEMBL1394218 | 0.70 | CRHBP (0.47) | UTS2R | |
| SCHEMBL325996 | 0.70 | MCHR1 (0.71) | MCHR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590969-A2 | THERAPEUTIC AGENTS 976 | AstraZeneca AB (SE) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004588-A2 | THERAPEUTIC AGENTS 976 | ASTRAZENECA AB (SE) | 2012-01-12 | — | — | WO | disclosed |