Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013412 | 0.83 | NPC1 (0.46) | MAPTPOLBALDH1A1KMT2ALMNA | |
| SCHEMBL3220798 | 0.79 | MAPT (0.57) | MAPTPOLBALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL3262032 | 0.74 | MAPT (1.00) | MAPTPOLBALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL3216521 | 0.73 | MAPT (0.78) | MAPTPOLBALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL3218859 | 0.73 | MAPT (0.81) | MAPTPOLBALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL2017246 | 0.72 | MAPT (0.43) | MAPTPOLBKMT2ATHRBRAB9A | |
| SCHEMBL13534756 | 0.72 | MAPT (0.60) | MAPTPOLBALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL3216164 | 0.72 | MAPT (0.59) | MAPTPOLBALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL3226076 | 0.72 | MAPT (0.58) | MAPTPOLBALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL2013353 | 0.71 | CACNA1G (0.45) | MAPTPOLBALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003197-A1 | MORPHOLINE DERIVATIVES USED AS ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2010-01-14 | — | — | WO | claimed |
| WO-2010003197-A1 | MORPHOLINE DERIVATIVES USED AS ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2010-01-14 | — | — | WO | disclosed |
| WO-2010003197-A1 | MORPHOLINE DERIVATIVES USED AS ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2010-01-14 | — | — | WO | disclosed |