Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 1/20 | 0.75 |
| ▸ | PDE4A | P27815 | 1/20 | 0.75 |
| ▸ | KDR | P35968 | 1/20 | 0.75 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL27445834 | 0.94 | HIF1A (0.86) | HIF1AMAPTPDE4AKDRCXCR4 | |
| Piperazine SCHEMBL5307572 | 0.94 | — | — | |
| Piperazine SCHEMBL27759910 | 0.88 | — | — | |
| Piperazine SCHEMBL27583112 | 0.88 | — | — | |
| Piperazine SCHEMBL27773496 | 0.88 | HIF1A (0.75) | HIF1AMAPTPDE4AKDRCXCR4 | |
| Piperazine SCHEMBL27402227 | 0.88 | — | — | |
| Aziridine SCHEMBL5484117 | 0.87 | — | — | |
| SCHEMBL5033222 | 0.87 | HIF1A (1.00) | HIF1AMAPTPDE4AKDRCXCR4 | |
| SCHEMBL577429 | 0.87 | HIF1A (1.00) | HIF1AMAPTPDE4AKDRCXCR4 | |
| SCHEMBL22003 | 0.87 | HIF1A (1.00) | HIF1AMAPTPDE4AKDRCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043416-A | Curable adhesive sheet | 琳得科株式会社 | 2024-05-14 | — | — | CN | disclosed |
| CN-118019819-A | Curable adhesive sheet and method for producing cured product | 琳得科株式会社 | 2024-05-10 | — | — | CN | disclosed |
| CN-113993958-B | Adhesive sheet for sealing device | 琳得科株式会社 | 2024-01-05 | — | — | CN | disclosed |
| CN-114555744-B | Adhesive composition and adhesive sheet | 琳得科株式会社 | 2023-09-15 | — | — | CN | disclosed |
| WO-2023054676-A1 | CURABLE ADHESIVE SHEET | リンテック株式会社 | 2023-04-06 | — | — | WO | disclosed |
| WO-2023054677-A1 | CURABLE ADHESIVE SHEET, AND METHOD FOR PRODUCING CURED PRODUCT | リンテック株式会社 | 2023-04-06 | — | — | WO | disclosed |
| WO-2023002970-A1 | CURABLE ADHESIVE COMPOSITION AND CURABLE ADHESIVE SHEET | リンテック株式会社 | 2023-01-26 | — | — | WO | disclosed |
| CN-115135736-A | Curable adhesive sheet for device | 琳得科株式会社 | 2022-09-30 | — | — | CN | disclosed |
| CN-114555744-A | Adhesive composition and adhesive sheet | 琳得科株式会社 | 2022-05-27 | — | — | CN | disclosed |
| CN-113993958-A | Adhesive sheet for sealing device | 琳得科株式会社 | 2022-01-28 | — | — | CN | disclosed |
| CN-113924341-A | Sealing sheet | 琳得科株式会社 | 2022-01-11 | — | — | CN | disclosed |
| US-8668983-B2 | Epoxy resin composition for fiber reinforced composite material | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2014-03-11 | — | — | US | disclosed |
| EP-2097481-B1 | EPOXY RESIN COMPOSITION FOR FIBER REINFORCED COMPOSITE MATERIAL | YOKOHAMA RUBBER CO LTD (JP) | 2012-10-10 | — | — | EP | disclosed |
| US-20100062211-A1 | EPOXY RESIN COMPOSITION FOR FIBER REINFORCED COMPOSITE MATERIAL | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2010-03-11 | — | — | US | disclosed |
| EP-2097481-A1 | EPOXY RESIN COMPOSITION FOR FIBER REINFORCED COMPOSITE MATERIAL | The Yokohama Rubber Co., Ltd. (JP) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008072769-A1 | EPOXY RESIN COMPOSITION FOR FIBER REINFORCED COMPOSITE MATERIAL | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2008-06-19 | — | — | WO | disclosed |