SCHEMBL577429

SCHEMBL577429

C1CNCCNCCNCCNCCN1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 1.00
MAPT P10636 1/20 1.00
PDE4A P27815 1/20 1.00
KDR P35968 1/20 1.00
CXCR4 P61073 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
ALDH1A1 P00352 1/20 0.50
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50
CYP2C9 P11712 1/20 0.50
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4299924 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL8199316 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL22003 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL7052601 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL5033222 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL2373879 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
Piperazine SCHEMBL734764 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL3999265 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL576335 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
Piperazine SCHEMBL8010246 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 445 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119874727-A Barium complex and preparation method and application thereof 中国科学院赣江创新研究院 2025-04-25 CN claimed
CN-118995178-A Functional surfactant for oil and gas field and preparation method thereof 陕西邦希化工有限公司 2024-11-22 CN claimed
US-20240139353-A1 METHODS OF TREATING CANCER Fusion Pharmaceuticals Inc. (CA) 2024-05-02 US claimed
CN-117181019-A Nitrogen-containing hybrid macrocyclic cycloparaffin polyamide composite membrane, and preparation method and application thereof 天津大学 2023-12-08 CN claimed
CN-116471853-A Perovskite solar cell modified by nitrogenous cyclic molecules 西北工业大学 2023-07-21 CN claimed
CN-114699930-B Polyazacyclic amide membrane for dye wastewater treatment and preparation method thereof 郑州大学 2023-04-14 CN claimed
WO-2023050008-A1 EGFRVIII-TARGETED COMPOUNDS AND USES THEREOF NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2023-04-06 WO claimed
WO-2023049985-A1 EGFRVIII-TARGETED COMPOUNDS AND USES THEREOF NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2023-04-06 WO claimed
US-20230052140-A1 IGF-1R MONOCLONAL ANTIBODIES AND USES THEREOF CENTRE FOR PROBE DEVELOPMENT AND COMMERCIALIZATION (CA) 2023-02-16 US claimed
CN-115364684-B High-flux positively-charged nanofiltration membrane and preparation method thereof 天津大学 2023-01-03 CN claimed
US-20040137638-A1 Superoxide dismutase mimetic metal complexes in which the metal can coordinate axial ligands; mobile phase comprising an excess of a salt of a coordinating anion in a solvent system GALERA THERAPEUTICS, LLC 2004-07-15 US claimed
US-20040122250-A1 Mesoporous organic-inorganic hybrid materials for separating gases CENTRE NATIONAL DE LA RECHERCHE-SCIENTIFIQUE (FR) 2004-06-24 US claimed
EP-1405066-A1 CHROMATOGRAPHY OF METAL COMPLEXES Metaphore Pharmaceuticals Inc. (US) 2004-04-07 EP claimed
EP-1347964-A2 TETRAETHER LIPID DERIVATIVES AND LIPOSOMES CONTAINING TETRAETHER LIPID DERIVATIVES AND LIPID AGGLOMERATES AND THE USE THEREOF Bernina Biosystems GmbH (DE) 2003-10-01 EP claimed
WO-2002071054-A1 CHROMATOGRAPHY OF METAL COMPLEXES METAPHORE PHARMACEUTICALS, INC. (US) 2002-09-12 WO claimed
WO-2002053554-A2 TETRAETHER LIPID DERIVATIVES AND LIPOSOMES CONTAINING TETRAETHER LIPID DERIVATIVES AND LIPID AGGLOMERATES AND THE USE THEREOF BERNINA BIOSYSTEMS GMBH (DE) 2002-07-11 WO claimed
US-6193950-B1 FOR DIAGNOSIS AND THERAPY SCHERING AG (DE) 2001-02-27 US claimed
US-5650136-A Cascade polymer bound complexing compounds, their complexes and conjugates, processes for their production, and pharmaceutical agents containing them SCHERING AKTIENGESELLSCHAFT (DE) 1997-07-22 US claimed
WO-1990007261-A2 PROCESS FOR PREPARING MONO-N-ALKYLATED POLYAZAMACROCYCLES THE DOW CHEMICAL COMPANY (US) 1990-07-12 WO claimed
US-4001212-A EXTRACT METAL IONS FROM SOLUTION AND COMPLEX E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-01-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040122250-A1 Mesoporous organic-inorganic hybrid materials for separating gases SCO2, IPO9, IPO4 HIF1A 3377/4885MAPT 4676/4885PDE4A 4882/4885
US-20240139353-A1 METHODS OF TREATING CANCER FGFR3, FGFR2, FGFR1 HIF1A 469/4885MAPT 2485/4885PDE4A 4810/4885
US-20230052140-A1 IGF-1R MONOCLONAL ANTIBODIES AND USES THEREOF IGF1R, IGFBP1, IGFBP2 HIF1A 398/4885MAPT 3641/4885PDE4A 4601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.