Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTR1E | P28566 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5395403 | 0.80 | CA1 (0.44) | MAPTNPSR1HTR1ES1PR3LMNA | |
| SCHEMBL5395406 | 0.79 | CA1 (0.43) | MAPTNPSR1HTR1ES1PR3LMNA | |
| SCHEMBL9110057 | 0.78 | HSD17B10 (0.48) | HSD17B10ACHEMAPTNPSR1HTR1E | |
| SCHEMBL6132931 | 0.76 | MAPT (0.49) | MAPTLMNACYP3A4MEN1CYP2C19 | |
| SCHEMBL17186779 | 0.75 | CYP1A2 (0.41) | MAPTMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL3227451 | 0.74 | MEN1 (0.58) | MAPTNPSR1HTR1ES1PR3LMNA | |
| SCHEMBL26218806 | 0.74 | MAPT (0.49) | HSD17B10ACHEMAPTNPSR1HTR1E | |
| SCHEMBL9812380 | 0.74 | HSD17B10 (0.52) | HSD17B10ACHEMAPTNPSR1HTR1E | |
| SCHEMBL28662620 | 0.73 | NPC1 (0.46) | HSD17B10ACHEMAPTNPSR1HTR1E | |
| SCHEMBL17109519 | 0.73 | ALDH1A1 (0.47) | HSD17B10ACHEMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028179-A1 | HETEROCYCLIC COMPOUNDS AS GATA MODULATORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-03-11 | — | — | WO | disclosed |