Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132759 | 0.80 | DRD2 (0.43) | KMT2AMEN1ADRB1SMN1; SMN2LMNA | |
| SCHEMBL6132388 | 0.80 | MAPT (0.43) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL6132525 | 0.79 | ADRB1 (0.61) | CYP3A4CYP2C9CYP2C19ADRB1 | |
| Hydrochloric Acid SCHEMBL6132311 | 0.78 | ADRB1 (0.59) | CYP3A4CYP2C9CYP2C19ADRB1 | |
| Hydrochloric Acid SCHEMBL6132929 | 0.77 | ENPP2 (0.50) | MAPTALDH1A1ENPP2KMT2AMEN1 | |
| SCHEMBL3260119 | 0.76 | HSD17B10 (0.42) | MAPTALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11229803 | 0.75 | NPC1 (0.45) | SIRT6ALDH1A1ENPP2KMT2AMEN1 | |
| SCHEMBL25366550 | 0.75 | SIRT6 (0.67) | MAPTSIRT6ALDH1A1GAAKMT2A | |
| SCHEMBL6132250 | 0.73 | SMN1; SMN2 (0.59) | MAPTALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL7294688 | 0.73 | CCR1 (0.52) | MAPTALDH1A1GAAENPP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |