Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | FES | P07332 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | LYN | P07948 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FER | P16591 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2182245 | 0.84 | CASP3 (0.50) | SMN1; SMN2L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL12414132 | 0.76 | CASP3 (0.62) | L3MBTL1KMT2AMEN1MAPTLMNA | |
| SCHEMBL14158668 | 0.74 | CASP3 (0.54) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL27794247 | 0.72 | MEN1 (0.58) | SMN1; SMN2L3MBTL1KMT2AMEN1RAB9A | |
| SCHEMBL12414151 | 0.71 | KDM4E (0.41) | L3MBTL1KMT2AMEN1KDM4ERAB9A | |
| SCHEMBL3251954 | 0.71 | MTOR (0.48) | SMN1; SMN2CSNK2A1CSNK2A2CSNK2BL3MBTL1 | |
| SCHEMBL12414149 | 0.70 | ANO1 (0.46) | KMT2AMEN1NPC1 | |
| SCHEMBL12831287 | 0.70 | KDM4E (0.44) | SMN1; SMN2L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL2180308 | 0.69 | ANO1 (0.45) | KMT2AMEN1 | |
| SCHEMBL2179899 | 0.69 | LMNA (0.43) | KMT2AMEN1LMNAHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025295-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-04 | — | — | WO | disclosed |