Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261576 | 1.00 | MGAM (0.31) | MGAM | |
| Pyrrolidine SCHEMBL2361768 | 0.85 | GBA1 (0.30) | — | |
| SCHEMBL5292632 | 0.71 | — | — | |
| SCHEMBL11500196 | 0.71 | MAPT (0.42) | — | |
| SCHEMBL16841659 | 0.70 | GUSB (0.46) | — | |
| SCHEMBL3261592 | 0.67 | — | — | |
| SCHEMBL12244538 | 0.67 | — | — | |
| SCHEMBL12529886 | 0.67 | — | — | |
| SCHEMBL9409695 | 0.66 | ALDH1A1 (0.40) | MGAM | |
| SCHEMBL20746301 | 0.65 | PDK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010049678-A2 | TREATMENT OF ENERGY UTILIZATION DISEASES | SUMMIT CORPORATION PLC (GB) | 2010-05-06 | — | — | WO | disclosed |
| WO-2010029313-A1 | ANTIINFECTIVE COMPOUNDS | SUMMIT CORPORATION PLC. (GB) | 2010-03-18 | — | — | WO | disclosed |
| WO-2010015815-A2 | COMPOUNDS FOR THE TREATMENT OF FLAVIVIRAL INFECTIONS | SUMMIT CORPORATION PLC (GB) | 2010-02-11 | — | — | WO | disclosed |