Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 6/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3260780 | 1.00 | PRCP (0.57) | PRCPSLC6A2SLC6A4SLC6A3DRD1 | |
| SCHEMBL1247171 | 0.87 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3HTR2ASMN1; SMN2 | |
| SCHEMBL2571100 | 0.87 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3DRD1HTR2A | |
| SCHEMBL503849 | 0.80 | SIGMAR1 (0.62) | PRCPSLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL29390302 | 0.80 | SIGMAR1 (0.62) | PRCPSLC6A2SLC6A4SLC6A3HTR2A | |
| Ammonia Solution, Strong SCHEMBL8210515 | 0.78 | SIGMAR1 (0.60) | PRCPSLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL30606845 | 0.78 | SIGMAR1 (0.60) | PRCPSLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL28025940 | 0.78 | SIGMAR1 (0.60) | PRCPSLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL23677287 | 0.78 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3HTR2ASMN1; SMN2 | |
| SCHEMBL395087 | 0.77 | GID4 (0.62) | SIGMAR1MAPK1BLMCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012812-A1 | BENZAZEPINES AND BENZAZOCINES AS SIGMA-RECEPTOR LIGANDES | Westfälische Wilhelms Universität Münster (DE) | 2010-02-04 | — | — | WO | disclosed |