Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 7/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.49 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263222 | 0.92 | LPL (0.47) | LPLLIPGF11HRH3LTA4H | |
| SCHEMBL3263221 | 0.92 | LPL (0.47) | LPLLIPGF11HRH3LTA4H | |
| SCHEMBL3264388 | 0.92 | LPL (0.47) | LPLLIPGF11HRH3LTA4H | |
| SCHEMBL18580899 | 0.90 | LPL (0.48) | LPLLIPGF11HRH3LTA4H | |
| SCHEMBL21755926 | 0.89 | HRH3 (0.58) | LPLLIPGF11HRH3LTA4H | |
| SCHEMBL18579804 | 0.87 | ALDH1A1 (0.49) | LPLLIPGF11HRH3LTA4H | |
| SCHEMBL21055138 | 0.87 | LPL (0.50) | LPLLIPGF11HRH3ESR2 | |
| SCHEMBL1428042 | 0.87 | LPL (0.44) | LPLLIPGF11HRH3LTA4H | |
| SCHEMBL3261155 | 0.85 | HRH3 (0.44) | LPLLIPGF11HRH3LTA4H | |
| SCHEMBL146568 | 0.85 | HRH3 (0.56) | LPLLIPGF11HRH3ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010189-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2010-01-28 | — | — | WO | disclosed |
| WO-2010010184-A1 | [1, 2, 4] TRIAZOLO [1, 5-A] PYRIDINES AS JAK INHIBITORS | GALAPAGOS NV (BE) | 2010-01-28 | — | — | WO | disclosed |