Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL8327293 | 1.00 | ALDH1A1 (0.60) | — | |
| Ethylene Glycol SCHEMBL8328945 | 1.00 | ALDH1A1 (0.60) | — | |
| Ethylene Glycol SCHEMBL8381661 | 1.00 | ALDH1A1 (0.60) | — | |
| Ethylene Glycol SCHEMBL5685968 | 0.95 | ALDH1A1 (0.55) | — | |
| Propanol SCHEMBL9313925 | 0.91 | ALDH1A1 (0.50) | — | |
| Alcohol SCHEMBL8330183 | 0.89 | — | — | |
| Alcohol SCHEMBL722166 | 0.89 | — | — | |
| Alcohol SCHEMBL11444793 | 0.89 | TSHR (0.75) | — | |
| Alcohol SCHEMBL1357723 | 0.89 | — | — | |
| Alcohol SCHEMBL11319836 | 0.89 | TSHR (0.75) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109201091-A | A kind of purification of water quality magnetic response type nucleocapsid photochemical catalyst and preparation method thereof | 南京理工大学 | 2019-01-15 | — | — | CN | claimed |
| CN-103480405-B | A kind of macropore carbonization Raney nickel and its preparation method and application | CHINA UNIVERSITY OF PETROLEUM (BEIJING) (CN) | 2015-11-18 | — | — | CN | claimed |
| CN-103480404-B | Macroporous iron carbide catalyst, and preparation method and application thereof | UNIV CHINA PETROLEUM BEIJING | 2015-05-06 | — | — | CN | claimed |
| CN-103480405-A | Macroporous carbonized nickel catalyst, and preparation method and application thereof | UNIV CHINA PETROLEUM BEIJING | 2014-01-01 | — | — | CN | claimed |
| CN-103480404-A | Macroporous iron carbide catalyst, and preparation method and application thereof | UNIV CHINA PETROLEUM BEIJING | 2014-01-01 | — | — | CN | claimed |
| WO-2013087547-A1 | METHOD FOR PRODUCING ALIPHATIC POLYESTERS | UHDE INVENTA-FISCHER GMBH (DE) | 2013-06-20 | — | — | WO | claimed |
| EP-4326737-A1 | SALTS AND CRYSTALLINE FORMS OF (3E) 3-[O-[(PHOSPHONOOXY)METHYL]OXIME]-PREGN-4-ENE-3, 20-DIONE AND RELATED USES | Neurotrauma Sciences LLC (US) | 2024-02-28 | — | — | EP | disclosed |
| US-20230210769-A1 | METHODS OF TREATMENT USING NICLOSAMIDE | SOFTHALE NV (BE) | 2023-07-06 | — | — | US | disclosed |
| US-11390768-B2 | Silver-organo-complex ink with high conductivity and inkjet stability | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2022-07-19 | — | — | US | disclosed |
| CN-114415470-A | Photosensitive resin layer of transfer photosensitive resin plate capable of being developed by water, preparation method of photosensitive resin layer and transfer photosensitive resin plate comprising photosensitive resin layer | 乐凯华光印刷科技有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114171456-A | Preparation method of pixel electrode, array substrate and display panel | TCL华星光电技术有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-113831437-A | Method for producing ultra-high molecular weight polymers in powder form | 印度石油有限公司 | 2021-12-24 | — | — | CN | disclosed |
| CN-214863556-U | Novel low temperature reaction cooling device | 合肥鼎材科技有限公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-1083409-C | Monomer recovery process for contaminated polymers | DU PONT (US) | 2002-04-24 | — | — | CN | disclosed |
| WO-2001091999-A1 | GLOSSY INK JET MEDIUM | IMAGE PRODUCTS GROUP LLC (US) | 2001-12-06 | — | — | WO | disclosed |
| US-5968848-A | SALT OF HYDROFLUORIC ACID AND A METALLIC-ION-FREE BASE SUCH AS AN ORGANIC AMINE | TOKYO OHKA KOGYO CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| CN-1222132-A | Monomer recovery process for contaminated polymers | DU PONT (US) | 1999-07-07 | — | — | CN | disclosed |
| US-5018160-A | Dye system for dye laser applications | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1991-05-21 | — | — | US | disclosed |
| US-4367699-A | Boiling liquid engine cooling system | EVC ASSOCIATES LIMITED PARTNERSHIP (US) | 1983-01-11 | — | — | US | disclosed |
| US-4052379-A | DYES FROM TRIFLUOROMETHYL-2-AMINOBENZOTHIAZOLE DIAZO COMPONENTS | EASTMAN KODAK COMPANY (US) | 1977-10-04 | — | — | US | disclosed |