Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL3261295 | 1.00 | — | — | |
| Ethylene Glycol SCHEMBL8327293 | 1.00 | ALDH1A1 (0.60) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 | |
| Ethylene Glycol SCHEMBL8381661 | 1.00 | ALDH1A1 (0.60) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 | |
| Ethylene Glycol SCHEMBL5685968 | 0.95 | ALDH1A1 (0.55) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 | |
| Propanol SCHEMBL9313925 | 0.91 | ALDH1A1 (0.50) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 | |
| Alcohol SCHEMBL8330183 | 0.89 | — | — | |
| Alcohol SCHEMBL722166 | 0.89 | — | — | |
| Alcohol SCHEMBL11444793 | 0.89 | TSHR (0.75) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 | |
| Alcohol SCHEMBL1357723 | 0.89 | — | — | |
| Alcohol SCHEMBL11319836 | 0.89 | TSHR (0.75) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6003987-A | Ink set recording apparatus and method using ink set having a dye that becomes insoluble when mixed with another dye | CANON KABUSHIKI KAISHA (JP) | 1999-12-21 | — | — | US | disclosed |