Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599738 | 0.78 | HCAR2 (0.63) | SMN1; SMN2LMNAHCAR2 | |
| SCHEMBL31475447 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2CA12CA9CA1CA2 | |
| SCHEMBL5107095 | 0.76 | PDE3B (0.40) | SMN1; SMN2ALDH1A1LMNAKDM4EHSD17B10 | |
| SCHEMBL3261535 | 0.74 | ALPL (0.54) | SMN1; SMN2ALDH1A1LMNARAB9AKDM4E | |
| SCHEMBL2725056 | 0.74 | — | — | |
| SCHEMBL1923718 | 0.72 | KDM4E (0.49) | SMN1; SMN2CA12CA9CA1CA2 | |
| SCHEMBL8720083 | 0.72 | SMN1; SMN2 (0.51) | SMN1; SMN2CA12CA9CA1CA2 | |
| SCHEMBL8010853 | 0.71 | PDE3B (0.39) | SMN1; SMN2ALDH1A1KDM4EHCAR2 | |
| SCHEMBL22191575 | 0.70 | ALK (0.58) | SMN1; SMN2ALDH1A1LMNAKDM4EHSD17B10 | |
| SCHEMBL3204772 | 0.70 | CYP4F2 (0.39) | SMN1; SMN2ALDH1A1LMNAKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |