Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | FPR1 | P21462 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860349 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2KDM4EALDH1A1CA12CA1 | |
| SCHEMBL3587984 | 0.84 | KDM4E (0.48) | SMN1; SMN2KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL28575636 | 0.83 | SMN1; SMN2 (0.45) | SMN1; SMN2KDM4EALDH1A1CA12CA1 | |
| SCHEMBL23930792 | 0.82 | ALPL (0.46) | SMN1; SMN2KDM4EALDH1A1CA12CA1 | |
| SCHEMBL877436 | 0.78 | HCAR2 (0.52) | KDM4EALDH1A1MEN1KMT2ADAO | |
| SCHEMBL12174907 | 0.78 | HCAR2 (0.47) | SMN1; SMN2LMNAKMT2ARAB9ADAO | |
| SCHEMBL5327425 | 0.77 | LMNA (0.56) | SMN1; SMN2KDM4EALDH1A1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL1371875 | 0.77 | HCAR2 (0.50) | KDM4EALDH1A1MEN1KMT2ADAO | |
| SCHEMBL6507956 | 0.77 | HCAR2 (0.46) | SMN1; SMN2LMNAKMT2ADAOHCAR2 | |
| SCHEMBL24968328 | 0.76 | ALDH1A1 (0.47) | SMN1; SMN2KDM4EALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1209807-A | 1-pyrazol-3-yl-ethyl-4-indol-3-yl piperdine as medicine acting on central nervous system | MERCK PATENT AG (DE) | 1999-03-03 | — | — | CN | disclosed |
| EP-0879234-A1 | 1-PYRAZOL-3-YL-ETHYL-4-INDOL-3-YL-PIPERIDINE USED AS MEDICINE ACTING ON THE CENTRAL NERVOUS SYSTEM | MERCK PATENT GmbH (DE) | 1998-11-25 | — | — | EP | disclosed |
| WO-1997027186-A1 | 1-PYRAZOL-3-YL-ETHYL-4-INDOL-3-YL-PIPERIDINE USED AS MEDICINE ACTING ON THE CENTRAL NERVOUS SYSTEM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1997-07-31 | — | — | WO | disclosed |