Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 6/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1715780 | 0.80 | KDM4C (0.54) | LMNATDP1KDM4ESCDRAB9A | |
| SCHEMBL2908569 | 0.78 | NPC1 (0.43) | LMNATDP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2908930 | 0.76 | ABCB1 (0.44) | LMNATDP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7439245 | 0.76 | ADRA1A (0.55) | ADRA1AADRA1BADRA1DKDM4EGLA | |
| SCHEMBL6197980 | 0.76 | ADRA1A (0.57) | ADRA1AADRA1BLMNAKDM4EGLA | |
| SCHEMBL1643649 | 0.73 | KDM4E (0.72) | ADRA1AADRA1BTDP1ADRA1DKDM4E | |
| SCHEMBL219602 | 0.73 | ADRA1A (0.55) | ADRA1AADRA1BLMNATDP1ADRA1D | |
| SCHEMBL1715462 | 0.73 | PTGS2 (0.46) | LMNATDP1KDM4ERAB9AKDM4C | |
| SCHEMBL1716106 | 0.73 | TDP1 (0.39) | ADRA1AADRA1BLMNATDP1ADRA1D | |
| SCHEMBL7873424 | 0.72 | ADRA1A (0.54) | ADRA1AADRA1BLMNATDP1ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |