Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 17/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1350231 | 0.87 | SLC6A9 (0.45) | SLC6A9MEN1GAAKMT2A | |
| SCHEMBL1350079 | 0.86 | SLC6A9 (0.41) | SLC6A9SLC6A5 | |
| SCHEMBL1347772 | 0.85 | SLC6A9 (0.53) | SLC6A9CYP2D6CYP2C19SLC6A5MEN1 | |
| SCHEMBL1349456 | 0.85 | SLC6A9 (0.52) | SLC6A9CYP2D6CYP2C19SLC6A5MEN1 | |
| SCHEMBL1350061 | 0.84 | SLC6A9 (0.42) | SLC6A9CYP2D6CYP2C19SLC6A5 | |
| SCHEMBL1350169 | 0.83 | SLC6A9 (0.54) | SLC6A9CYP2D6CYP2C19SLC6A5MEN1 | |
| SCHEMBL1348082 | 0.81 | SLC6A9 (0.43) | SLC6A9CYP2D6CYP2C19SLC6A5 | |
| SCHEMBL1349947 | 0.81 | KLRK1 (0.41) | SLC6A9 | |
| SCHEMBL1350069 | 0.80 | SLC6A9 (0.46) | SLC6A9MEN1GAAKMT2A | |
| SCHEMBL3264199 | 0.80 | SLC6A9 (0.47) | SLC6A9CYP2D6CYP2C19SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010020548-A1 | GLYT1 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-02-25 | — | — | WO | disclosed |