Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 9/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 9/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3228883 | 0.80 | ADORA1 (0.40) | ADORA3ADORA2AADORA1GPR183SYK | |
| SCHEMBL3228889 | 0.78 | ADORA1 (0.39) | ADORA3ADORA2AADORA1GPR183SYK | |
| SCHEMBL3236210 | 0.78 | GABBR2 (0.51) | GBA1GABBR2GABBR1PDGFRBPDGFRA | |
| SCHEMBL3229963 | 0.77 | ADORA1 (0.38) | ADORA3ADORA2AADORA1GPR183SYK | |
| SCHEMBL16391919 | 0.74 | ABCG2 (0.49) | ADORA3ADORA2AADORA1GPR183GBA1 | |
| SCHEMBL15102267 | 0.73 | ADORA3 (0.55) | ADORA3ADORA2AADORA1GPR183GBA1 | |
| SCHEMBL15124922 | 0.73 | ADORA3 (0.55) | ADORA3ADORA2AADORA1GPR183GBA1 | |
| SCHEMBL29560792 | 0.73 | ADORA3 (0.55) | ADORA3ADORA2AADORA1GPR183GBA1 | |
| SCHEMBL29389493 | 0.72 | MEN1 (0.47) | ADORA3ADORA2AADORA1GBA1GABBR2 | |
| SCHEMBL16391827 | 0.71 | GBA1 (0.49) | ADORA3ADORA2AADORA1GPR183GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028179-A1 | HETEROCYCLIC COMPOUNDS AS GATA MODULATORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-03-11 | — | — | WO | claimed |