SCHEMBL3261732

SCHEMBL3261732

C=CC(=O)C([C]=O)C(=O)C=C

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
FGFR4 P22455 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8998334 0.72
SCHEMBL11123902 0.72
SCHEMBL4843693 0.72
SCHEMBL1924525 0.67 LMNA (0.44) LMNAALDH1A1TSHRFGFR4
SCHEMBL27536714 0.67 GRIK1 (0.31)
SCHEMBL10622814 0.67
SCHEMBL27603680 0.65 LMNA (0.41) LMNAALDH1A1TSHRFGFR4
SCHEMBL8620304 0.65
SCHEMBL9747332 0.65 LMNA (0.41) LMNAALDH1A1TSHRFGFR4
SCHEMBL27861881 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7683041-B2 Microgel particles for the delivery of bioactive materials THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-03-23 US claimed
US-20060223776-A1 Microgel particles for the delivery of bioactive materials THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-10-05 US claimed
EP-1490083-A1 MICROGEL PARTICLES FOR THE DELIVERY OF BIOACTIVE MATERIALS The Regents of the University of California (US) 2004-12-29 EP claimed
US-20030211158-A1 Microgel particles for the delivery of bioactive materials UNITED STATES DEPARTMENT OF ENERGY 2003-11-13 US claimed
WO-2003082316-A1 MICROGEL PARTICLES FOR THE DELIVERY OF BIOACTIVE MATERIALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-10-09 WO claimed
US-11293915-B2 Bio-adhesive gels and methods of use CORNELL UNIVERSITY (US) 2022-04-05 US disclosed
US-20170074861-A1 BIO-ADHESIVE GELS AND METHODS OF USE CORNELL UNIVERSITY 2017-03-16 US disclosed
WO-2015172073-A1 BIO-ADHESIVE GELS AND METHODS OF USE CORNELL UNIVERSITY (US) 2015-11-12 WO disclosed
EP-2900783-A1 DEHYDRATED GEL COMPOSITIONS AND METHODS OF USING THE SAME Halliburton Energy Services, Inc. (US) 2015-08-05 EP disclosed
US-7683041-B2 Microgel particles for the delivery of bioactive materials THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-03-23 US disclosed
US-7683041-B2 Microgel particles for the delivery of bioactive materials THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-03-23 US disclosed
EP-2148701-A2 IMAGING CONTRAST AGENTS USING NANOPARTICLES Carestream Health, Inc. (US) 2010-02-03 EP disclosed
US-7056901-B2 Microgel particles for the delivery of bioactive materials THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-06-06 US disclosed
US-7056901-B2 Microgel particles for the delivery of bioactive materials THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-06-06 US disclosed
EP-1490083-A1 MICROGEL PARTICLES FOR THE DELIVERY OF BIOACTIVE MATERIALS The Regents of the University of California (US) 2004-12-29 EP disclosed
EP-1490083-A1 MICROGEL PARTICLES FOR THE DELIVERY OF BIOACTIVE MATERIALS The Regents of the University of California (US) 2004-12-29 EP disclosed
US-20030211158-A1 Microgel particles for the delivery of bioactive materials UNITED STATES DEPARTMENT OF ENERGY 2003-11-13 US disclosed
US-20030211158-A1 Microgel particles for the delivery of bioactive materials UNITED STATES DEPARTMENT OF ENERGY 2003-11-13 US disclosed
WO-2003082316-A1 MICROGEL PARTICLES FOR THE DELIVERY OF BIOACTIVE MATERIALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-10-09 WO disclosed
WO-2003082316-A1 MICROGEL PARTICLES FOR THE DELIVERY OF BIOACTIVE MATERIALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211158-A1 Microgel particles for the delivery of bioactive materials CTSE, CHMP4B, GAA LMNA 519/4885ALDH1A1 2991/4885TSHR 4770/4885
US-20060223776-A1 Microgel particles for the delivery of bioactive materials CTSE, CHMP4B, GAA LMNA 519/4885ALDH1A1 2991/4885TSHR 4770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.