Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 2/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1971605 | 0.92 | CNR2 (0.38) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL3275899 | 0.84 | HTR2C (0.49) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL1965541 | 0.76 | KMT2A (0.52) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL3275051 | 0.71 | HTR2C (0.45) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL303519 | 0.71 | HTR2C (0.45) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL309786 | 0.71 | CNR2 (0.38) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL303078 | 0.71 | CNR2 (0.55) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL302217 | 0.70 | HTR2C (0.47) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL303627 | 0.67 | HTR2C (0.39) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL3275347 | 0.67 | HTR2C (0.54) | HTR2CHTR1AHTR2AHTR7DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030835-A2 | PHARMACEUTICAL COMPOSITIONS OF AN SRC KINASE INHIBITOR AND AN AROMATASE INHIBITOR | WYETH LLC (US) | 2010-03-18 | — | — | WO | disclosed |
| WO-2010023446-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | disclosed |