Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968022 | 0.81 | KMT2A (0.48) | HTR2CDRD3HTR1AHTR2AHTR7 | |
| SCHEMBL1966251 | 0.81 | HTR2C (0.49) | HTR2CDRD3HTR1AHTR2AHTR7 | |
| SCHEMBL302774 | 0.78 | HTR2C (0.58) | HTR2CDRD3HTR1AHTR2AHTR7 | |
| SCHEMBL3275347 | 0.76 | HTR2C (0.54) | HTR2CDRD3HTR1AHTR2AHTR7 | |
| SCHEMBL304739 | 0.75 | CNR2 (0.43) | HTR2CDRD3HTR1AHTR2AHTR7 | |
| SCHEMBL1966404 | 0.74 | DRD4 (0.51) | HTR2CDRD3HTR1AHTR2AHTR7 | |
| SCHEMBL306481 | 0.70 | PARP1 (0.42) | KMT2AMEN1POLBDRD4PKM | |
| SCHEMBL2210474 | 0.70 | MEN1 (0.42) | KMT2AMEN1POLBPKMPRNP | |
| SCHEMBL318081 | 0.68 | DRD4 (0.39) | HTR2CDRD3HTR1AHTR2AHTR7 | |
| SCHEMBL1971605 | 0.68 | CNR2 (0.38) | HTR2CDRD3HTR1AHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500835-A | — | — | 2012-01-12 | — | — | JP | claimed |
| EP-2334637-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | Xention Limited (GB) | 2011-06-22 | — | — | EP | claimed |
| WO-2010023446-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | claimed |