Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | AHR | P35869 | 1/20 | 0.58 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6291031 | 0.76 | MAPT (1.00) | MAPTKMT2AMEN1KDM4EGAA | |
| SCHEMBL3264986 | 0.75 | MAPT (0.75) | MAPTKMT2AMEN1KDM4EGAA | |
| SCHEMBL5341593 | 0.74 | AHR (1.00) | MAPTKMT2AMEN1KDM4EGAA | |
| SCHEMBL20120113 | 0.74 | KDM4E (0.73) | MAPTKMT2AMEN1KDM4EGAA | |
| SCHEMBL6993605 | 0.74 | MAPT (0.52) | MAPTKMT2AMEN1KDM4EGAA | |
| SCHEMBL4423600 | 0.73 | MAPT (0.65) | MAPTKMT2AMEN1KDM4EGAA | |
| SCHEMBL9974571 | 0.73 | KIF11 (0.71) | MAPTKMT2AMEN1KDM4EGAA | |
| SCHEMBL29363363 | 0.73 | KIF11 (0.71) | MAPTKMT2AMEN1KDM4EGAA | |
| SCHEMBL19871249 | 0.71 | MAPT (0.63) | MAPTKMT2AMEN1KDM4EGAA | |
| SCHEMBL201782 | 0.70 | CYP2A6 (0.43) | MAPTTSHRALDH1A1ATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012397-A1 | N-(INDOL-3-YLALKYL)(HETERO)ARYLAMIDE DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-04 | — | — | WO | claimed |
| WO-2010012397-A1 | N-(INDOL-3-YLALKYL)(HETERO)ARYLAMIDE DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-04 | — | — | WO | disclosed |