Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.60 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262057 | 1.00 | GPR119 (0.60) | GPR119GPR183KCNH2CYP3A4CYP2C19 | |
| SCHEMBL149470 | 0.87 | GPR119 (0.64) | GPR119GPR183KCNH2 | |
| SCHEMBL149471 | 0.87 | GPR119 (0.64) | GPR119GPR183KCNH2 | |
| SCHEMBL19450725 | 0.82 | GPR119 (0.72) | GPR119GPR183 | |
| SCHEMBL6118208 | 0.81 | GPR119 (0.67) | GPR119GPR183KCNH2 | |
| SCHEMBL3261136 | 0.81 | GPR119 (0.59) | GPR119GPR183KCNH2 | |
| SCHEMBL3261138 | 0.81 | GPR119 (0.59) | GPR119GPR183KCNH2 | |
| SCHEMBL121348 | 0.80 | GPR119 (0.52) | GPR119GPR183KCNH2CYP3A4CYP2C19 | |
| SCHEMBL461916 | 0.80 | GPR119 (0.61) | GPR119GPR183KCNH2 | |
| SCHEMBL461917 | 0.80 | GPR119 (0.61) | GPR119GPR183KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010004345-A1 | PIPERIDINYL GPCR AGONISTS | PROSIDION LIMITED (GB) | 2010-01-14 | — | — | WO | disclosed |