Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.61 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461917 | 1.00 | GPR119 (0.61) | GPR119GPR183LMNAMAPTKCNH2 | |
| SCHEMBL149471 | 0.82 | GPR119 (0.64) | GPR119GPR183LMNAMAPTKCNH2 | |
| SCHEMBL3261136 | 0.81 | GPR119 (0.59) | GPR119GPR183KCNH2 | |
| SCHEMBL1103886 | 0.80 | GPR119 (0.61) | GPR119GPR183LMNAMAPTKCNH2 | |
| SCHEMBL384918 | 0.80 | GPR119 (0.73) | GPR119GPR183LMNAMAPTKCNH2 | |
| SCHEMBL19450725 | 0.80 | GPR119 (0.72) | GPR119GPR183LMNAMAPT | |
| SCHEMBL3262057 | 0.80 | GPR119 (0.60) | GPR119GPR183KCNH2 | |
| SCHEMBL3262064 | 0.80 | GPR119 (0.60) | GPR119GPR183KCNH2 | |
| SCHEMBL19434962 | 0.79 | GPR119 (0.71) | GPR119GPR183LMNAMAPTKCNH2 | |
| SCHEMBL14723499 | 0.78 | GPR119 (0.69) | GPR119GPR183LMNAMAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |