Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13858518 | 0.85 | LMNA (0.82) | LMNAPDE4DALDH1A1KDM4EHPGD | |
| SCHEMBL3264753 | 0.85 | LMNA (0.61) | LMNAPDE4DALDH1A1KDM4EHPGD | |
| SCHEMBL3390032 | 0.84 | ALDH1A1 (0.65) | LMNAPDE4DALDH1A1KDM4EHPGD | |
| SCHEMBL3262371 | 0.81 | PDE4D (0.60) | LMNAPDE4DALDH1A1KDM4EHPGD | |
| SCHEMBL3263025 | 0.75 | PDE4D (0.60) | LMNAPDE4DALDH1A1KDM4EHPGD | |
| SCHEMBL17295099 | 0.75 | LMNA (0.49) | LMNAPDE4DALDH1A1KDM4EHPGD | |
| SCHEMBL17290333 | 0.75 | LMNA (0.49) | LMNAPDE4DALDH1A1KDM4EHPGD | |
| SCHEMBL27848785 | 0.75 | PDE4D (0.75) | LMNAPDE4DALDH1A1KDM4EHPGD | |
| SCHEMBL3611588 | 0.74 | LMNA (0.74) | LMNAPDE4DALDH1A1KDM4EHPGD | |
| SCHEMBL7732 | 0.74 | ALDH1A1 (0.58) | PDE4DALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |