Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114494 | 0.84 | GAA (0.37) | GAA | |
| SCHEMBL10722443 | 0.84 | ALDH1A1 (0.42) | GAATDP1 | |
| SCHEMBL11688370 | 0.84 | TDP1 (0.36) | GAATDP1 | |
| SCHEMBL27393839 | 0.84 | PDE4A (0.39) | PDE4AHSP90AA1GAA | |
| SCHEMBL25403257 | 0.80 | PDE4A (0.36) | PDE4A | |
| SCHEMBL25403255 | 0.80 | PDE4A (0.36) | PDE4A | |
| SCHEMBL571829 | 0.77 | PDE4A (0.37) | PDE4AGAA | |
| SCHEMBL15381134 | 0.76 | PDE4A (0.47) | PDE4AHSP90AA1 | |
| SCHEMBL29391673 | 0.76 | PDE4A (0.47) | PDE4AHSP90AA1 | |
| SCHEMBL11032177 | 0.75 | PDE4A (0.38) | PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025499-A1 | ENZYMES AND METHODS FOR DEGRADING S-TRIAZINES AND DIAZINES | COMMONWEALTH SCIENTIFIC INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-03-11 | — | — | WO | disclosed |
| WO-2010005384-A1 | KETONE PYRIDINE ANALOGUES AND THEIR USE IN THE TREATMENT OF CARDIOVASCULAR DISORDERS | ASTRAZENECA AB (SE) | 2010-01-14 | — | — | WO | disclosed |
| US-20090026135-A1 | MIXED BACTERIAL CULTURE FOR ATRAZINE DEGRADATION | RUDJER BOSKOVIC INSTITUTE (HR) | 2009-01-29 | — | — | US | disclosed |