Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25403257 | 1.00 | PDE4A (0.36) | PDE4A | |
| SCHEMBL3262195 | 0.80 | PDE4A (0.41) | PDE4A | |
| SCHEMBL27393839 | 0.77 | PDE4A (0.39) | PDE4A | |
| SCHEMBL26110169 | 0.72 | ALDH1A1 (0.36) | — | |
| SCHEMBL15381134 | 0.69 | PDE4A (0.47) | PDE4A | |
| SCHEMBL29391673 | 0.69 | PDE4A (0.47) | PDE4A | |
| SCHEMBL30075793 | 0.69 | IDH1 (0.48) | — | |
| SCHEMBL11032177 | 0.68 | PDE4A (0.38) | PDE4A | |
| SCHEMBL571829 | 0.67 | PDE4A (0.37) | PDE4A | |
| SCHEMBL571574 | 0.64 | MAPT (0.51) | PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051301-A1 | MUTANT IDH1 AND IDH2 INHIBITOR AND APPLICATION THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2025-02-13 | — | — | US | disclosed |
| WO-2023174235-A1 | MUTANT IDH1 AND IDH2 INHIBITOR AND APPLICATION THEREOF | 贝达药业股份有限公司 | 2023-09-21 | — | — | WO | disclosed |
| WO-2022095756-A1 | MUTANT IDH1 AND IDH2 INHIBITOR AND APPLICATION THEREOF | 贝达药业股份有限公司 | 2022-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051301-A1 | MUTANT IDH1 AND IDH2 INHIBITOR AND APPLICATION THEREOF | IDH1, IDH2, IDH3B | PDE4A 4145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.