Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | PARG | Q86W56 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 4/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584423 | 0.81 | MAPT (0.44) | IDO1TDO2IRAK4LPLLIPG | |
| SCHEMBL6919556 | 0.78 | IRAK4 (0.46) | IDO1TDO2IRAK4LPLLIPG | |
| SCHEMBL14658864 | 0.77 | L3MBTL1 (0.43) | IDO1TDO2CSF1RPRMT5WDR77 | |
| SCHEMBL30820850 | 0.77 | L3MBTL1 (0.43) | IDO1TDO2CSF1RPRMT5WDR77 | |
| SCHEMBL31037319 | 0.75 | KDM4E (0.48) | IDO1TDO2PARGCSF1RPRMT5 | |
| SCHEMBL3263196 | 0.75 | KDM4E (0.48) | IDO1TDO2PARGCSF1RPRMT5 | |
| SCHEMBL5986479 | 0.74 | CYP3A4 (0.48) | TDO2PARGALDH1A1KMT2A | |
| SCHEMBL14238895 | 0.72 | IDO1 (0.40) | IDO1TDO2PRMT5WDR77ALDH1A1 | |
| SCHEMBL149215 | 0.72 | IDO1 (0.38) | IDO1TDO2CSF1RPRMT5WDR77 | |
| SCHEMBL26170011 | 0.72 | IRAK4 (0.44) | IDO1TDO2CSF1RPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010020366-A1 | AZABICYCLIC SUBSTITUTED 5-AMINOPYRAZOLES AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-25 | — | — | WO | disclosed |
| WO-2010020366-A1 | AZABICYCLIC SUBSTITUTED 5-AMINOPYRAZOLES AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-25 | — | — | WO | disclosed |