Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 3/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL758753 | 0.83 | — | — | |
| SCHEMBL23870420 | 0.79 | ALDH1A1 (0.50) | TSHRALDH1A1MAPK1TDP1SMN1; SMN2 | |
| SCHEMBL15044554 | 0.79 | ALDH1A1 (0.50) | TSHRALDH1A1MAPK1TDP1SMN1; SMN2 | |
| SCHEMBL11141754 | 0.79 | ALDH1A1 (0.50) | TSHRALDH1A1MAPK1TDP1SMN1; SMN2 | |
| SCHEMBL12849273 | 0.78 | TSHR (0.48) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL28616756 | 0.76 | TSHR (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL8376831 | 0.75 | TSHR (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL26075410 | 0.75 | TSHR (0.50) | TSHRALDH1A1MAPK1TDP1SMN1; SMN2 | |
| SCHEMBL21664183 | 0.75 | TERT (0.37) | TSHRSMN1; SMN2MAPT | |
| SCHEMBL22430280 | 0.75 | TERT (0.37) | TSHRSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004554-A1 | ALDEHYDE COMPOUNDS AS INHIBITORS OF DUST MITE GROUP 1 PEPTIDASE ALLERGEN AND THEIR USE | ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) | 2012-01-12 | — | — | WO | disclosed |