Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118297 | 0.87 | MC4R (0.48) | RAB9ANPC1GABRA1GABRG2GABRB3 | |
| SCHEMBL3118314 | 0.87 | MC4R (0.48) | RAB9ANPC1GABRA1GABRG2GABRB3 | |
| SCHEMBL3124488 | 0.86 | MC4R (0.47) | RAB9ANPC1GABRA1GABRG2GABRB3 | |
| SCHEMBL3119512 | 0.76 | RAB9A (0.53) | RAB9ANPC1GABRA1GABRG2GABRB3 | |
| SCHEMBL3115322 | 0.76 | MC4R (0.52) | RAB9ANPC1GABRA1GABRG2GABRB3 | |
| SCHEMBL3262813 | 0.74 | MAPT (0.49) | NPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3262807 | 0.74 | MAPT (0.49) | NPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3122404 | 0.73 | MAPT (0.55) | NPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3119575 | 0.73 | MAPT (0.55) | NPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3122387 | 0.73 | MAPT (0.55) | NPC1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035032-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |