Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831554 | 0.80 | AOC3 (0.57) | AOC3GAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL20644495 | 0.79 | PTPN5 (0.40) | AOC3ALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL28028701 | 0.79 | AOC3 (0.59) | AOC3GAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL24015547 | 0.79 | ALDH1A1 (0.40) | AOC3ALDH1A1MAPTTSHRTDP1 | |
| SCHEMBL327629 | 0.78 | AOC3 (0.63) | AOC3GAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7932298 | 0.78 | ALDH1A1 (0.48) | AOC3GAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2517919 | 0.76 | AOC3 (0.61) | AOC3GAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL17660055 | 0.76 | AOC3 (0.61) | AOC3GAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL4372787 | 0.76 | AOC3 (0.61) | AOC3GAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL615718 | 0.76 | AOC3 (0.61) | AOC3GAAALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030787-A1 | ESTROGEN RECEPTOR LIGANDS | RADIUS HEALTH, INC. (US) | 2010-03-18 | — | — | WO | disclosed |