Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 6/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | TEK | Q02763 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30877517 | 0.85 | DGAT1 (0.44) | DGAT1NPC1 | |
| SCHEMBL28496046 | 0.80 | DGAT1 (0.38) | DGAT1NPC1 | |
| SCHEMBL17394885 | 0.80 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL16611601 | 0.79 | DGAT1 (0.40) | DGAT1NPC1 | |
| SCHEMBL28624418 | 0.79 | DGAT1 (0.37) | DGAT1NPC1 | |
| SCHEMBL28912548 | 0.79 | DGAT1 (0.34) | DGAT1NPC1 | |
| SCHEMBL10200583 | 0.79 | DGAT1 (0.34) | DGAT1NPC1 | |
| SCHEMBL30877301 | 0.79 | DGAT1 (0.34) | DGAT1NPC1 | |
| SCHEMBL28627973 | 0.76 | DGAT1 (0.33) | DGAT1NPC1 | |
| SCHEMBL29057679 | 0.76 | DGAT1 (0.34) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010005528-A2 | PYRROLOPYRIDINE CARBOXYLIC ACID DERIVATIVES | IRONWOOD PHARMACEUTICALS INCORPORATED (US) | 2010-01-14 | — | — | WO | claimed |