Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.37 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28496046 | 0.85 | DGAT1 (0.38) | DGAT1NPC1 | |
| SCHEMBL30877301 | 0.80 | DGAT1 (0.34) | DGAT1NPC1 | |
| SCHEMBL28912548 | 0.80 | DGAT1 (0.34) | DGAT1NPC1 | |
| SCHEMBL10200583 | 0.80 | DGAT1 (0.34) | DGAT1NPC1 | |
| SCHEMBL16611601 | 0.80 | DGAT1 (0.40) | DGAT1NPC1 | |
| SCHEMBL18031349 | 0.79 | MAPK14 (0.38) | DGAT1NPC1 | |
| SCHEMBL3262382 | 0.79 | DGAT1 (0.34) | DGAT1NPC1 | |
| SCHEMBL28627973 | 0.78 | DGAT1 (0.33) | DGAT1NPC1 | |
| SCHEMBL29862373 | 0.76 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL3526518 | 0.76 | NPC1 (0.37) | DGAT1F2RL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215861-B | Aromatic heterocycle substituted alkyne compound and preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-115215861-A | Aromatic heterocycle substituted alkyne compound and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-113164459-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2021-07-23 | — | — | CN | disclosed |