Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1411990 | 0.89 | MEN1 (0.33) | MEN1LMNAKMT2ACTDSP1CHRM2 | |
| SCHEMBL6114044 | 0.87 | ALDH1A1 (0.33) | — | |
| SCHEMBL5958093 | 0.86 | ALDH1A1 (0.36) | — | |
| SCHEMBL1681849 | 0.86 | ALDH1A1 (0.36) | — | |
| SCHEMBL12950085 | 0.86 | ALDH1A1 (0.36) | — | |
| SCHEMBL10861022 | 0.86 | ALDH1A1 (0.36) | — | |
| SCHEMBL10335254 | 0.86 | ALDH1A1 (0.36) | — | |
| SCHEMBL2959769 | 0.84 | MEN1 (0.46) | MEN1LMNAKMT2ACTDSP1CHRM2 | |
| SCHEMBL15628015 | 0.83 | MEN1 (0.31) | MEN1LMNAKMT2ACTDSP1CHRM2 | |
| SCHEMBL24065927 | 0.82 | CHRM2 (0.34) | MEN1LMNAKMT2ACTDSP1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643439-B1 | LUBRICATING COMPOSITION CONTAINING 1,3-DIOXOLANE-4-METHANOL COMPOUNDS AS ANTIWEAR ADDITIVES | CHEVRON ORONITE CO (US) | 2014-12-17 | — | — | EP | claimed |
| EP-2643439-A2 | LUBRICATING COMPOSITION CONTAINING 1,3-DIOXOLANE-4-METHANOL COMPOUNDS AS ANTIWEAR ADDITIVES | Chevron Oronite Company LLC (US) | 2013-10-02 | — | — | EP | claimed |
| US-8349777-B2 | Lubricating composition containing 1,3-dioxolane-4-methanol compounds as antiwear additives | CHEVRON ORONITE COMPANY LLC (US) | 2013-01-08 | — | — | US | claimed |
| WO-2012071154-A2 | LUBRICATING COMPOSITION CONTAINING 1,3-DIOXOLANE-4-METHANOL COMPOUNDS AS ANTIWEAR ADDITIVES | CHEVRON ORONITE COMPANY LLC (US) | 2012-05-31 | — | — | WO | claimed |
| US-20120129744-A1 | LUBRICATING COMPOSITION CONTAINING 1,3-DIOXOLANE-4-METHANOL COMPOUNDS AS ANTIWEAR ADDITIVES | CHEVRON ORONITE COMPANY LLC | 2012-05-24 | — | — | US | claimed |
| US-9388105-B2 | Production of hydroxy ether hydrocarbons by liquid phase hydrogenolysis of cyclic acetals or cyclic ketals | EASTMAN CHEMICAL COMPANY (US) | 2016-07-12 | — | — | US | disclosed |
| US-9382179-B2 | Nickel modified catalyst for the production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals | EASTMAN CHEMICAL COMPANY (US) | 2016-07-05 | — | — | US | disclosed |
| US-9056313-B2 | Catalysts for the production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals | EASTMAN CHEMICAL COMPANY (US) | 2015-06-16 | — | — | US | disclosed |
| US-9000229-B2 | Production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals | EASTMAN CHEMICAL COMPANY (US) | 2015-04-07 | — | — | US | disclosed |
| EP-2643439-B1 | LUBRICATING COMPOSITION CONTAINING 1,3-DIOXOLANE-4-METHANOL COMPOUNDS AS ANTIWEAR ADDITIVES | CHEVRON ORONITE CO (US) | 2014-12-17 | — | — | EP | disclosed |
| US-20140303404-A1 | NICKEL MODIFIED CATALYST FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS | EASTMAN CHEMICAL COMPANY (US) | 2014-10-09 | — | — | US | disclosed |
| US-8829229-B2 | Polyol ethers and process for making them | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-09-09 | — | — | US | disclosed |
| US-20120330068-A1 | NICKEL MODIFIED CATALYST FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | US | disclosed |
| WO-2012177484-A1 | CATALYSTS FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012177469-A1 | PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY LIQUID PHASE HYDROGENOLYSIS OF CYCLIC ACETALS OR CYCLIC KETALS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012177602-A1 | PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012071154-A2 | LUBRICATING COMPOSITION CONTAINING 1,3-DIOXOLANE-4-METHANOL COMPOUNDS AS ANTIWEAR ADDITIVES | CHEVRON ORONITE COMPANY LLC (US) | 2012-05-31 | — | — | WO | disclosed |
| US-20120129744-A1 | LUBRICATING COMPOSITION CONTAINING 1,3-DIOXOLANE-4-METHANOL COMPOUNDS AS ANTIWEAR ADDITIVES | CHEVRON ORONITE COMPANY LLC | 2012-05-24 | — | — | US | disclosed |
| WO-2010027663-A1 | POLYOL ETHERS AND PROCESS FOR MAKING THEM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-03-11 | — | — | WO | disclosed |
| US-20100048940-A1 | reductive etherification of a polyol with an aldehyde or ketone using a hydrogenation catalyt; resulting compounds have use as solvents, surfactants, degreasers, wetting agents, emulsifying agents, lubricants, and intermediates for surfactants; polyols can be from renewable raw materials | DOW GLOBAL TECHNOLOGIES LLC | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120330068-A1 | NICKEL MODIFIED CATALYST FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS | KAT5, HRH3, KAT8 | MEN1 632/4885LMNA 2124/4885KMT2A 101/4885 |
| US-20100048940-A1 | reductive etherification of a polyol with an aldehyde or ketone using a hydrogenation catalyt; resulting compounds have use as solvents, surfactants, degreasers, wetting agents, emulsifying agents, lubricants, and intermediates for surfactants; polyols can be from renewable raw materials | RNF114, USP14, USP13 | MEN1 4554/4885LMNA 3728/4885KMT2A 1606/4885 |
| US-20140303404-A1 | NICKEL MODIFIED CATALYST FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS | KAT5, HRH3, KAT8 | MEN1 632/4885LMNA 2124/4885KMT2A 101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.