Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.46 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.91 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20516489 | 0.95 | MAPK1 (1.00) | MAPK1NOD2ALDH1A1THRBESR1 | |
| SCHEMBL14520991 | 0.95 | MAPK1 (1.00) | MAPK1NOD2ALDH1A1THRBESR1 | |
| SCHEMBL57603 | 0.95 | MAPK1 (1.00) | MAPK1NOD2ALDH1A1THRBESR1 | |
| SCHEMBL15504324 | 0.95 | MAPK1 (1.00) | MAPK1NOD2ALDH1A1THRBESR1 | |
| SCHEMBL13575286 | 0.95 | MAPK1 (1.00) | MAPK1NOD2ALDH1A1THRBESR1 | |
| SCHEMBL6552473 | 0.95 | MAPK1 (1.00) | MAPK1NOD2ALDH1A1THRBESR1 | |
| SCHEMBL57604 | 0.95 | MAPK1 (1.00) | MAPK1NOD2ALDH1A1THRBESR1 | |
| N-Acetylglucosamine SCHEMBL28342076 | 0.93 | MAPK1 (0.95) | MAPK1NOD2ALDH1A1THRBESR1 | |
| SCHEMBL23247948 | 0.84 | MAPK1 (0.80) | MAPK1NOD2ALDH1A1THRBESR1 | |
| SCHEMBL31124790 | 0.84 | MAPK1 (0.80) | MAPK1NOD2ALDH1A1THRBESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100006801-A1 | Sugar derivatives and application of same | GREEN SCIENCE MATERIAL, INC. (JP) | 2010-01-14 | — | — | US | claimed |
| US-8350024-B2 | Sugar derivatives and application of same | GREEN SCIENCE MATERIAL, INC. (JP) | 2013-01-08 | — | — | US | disclosed |
| US-20100006801-A1 | Sugar derivatives and application of same | GREEN SCIENCE MATERIAL, INC. (JP) | 2010-01-14 | — | — | US | disclosed |