Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11808361 | 0.88 | CHRNB2 (0.35) | TSHRCHRNB2CHRNB4CHRNA4 | |
| SCHEMBL11165734 | 0.84 | CHRNB2 (0.42) | ALDH1A1CHRNB2CHRNB4CHRNA4LMNA | |
| SCHEMBL4147215 | 0.84 | CES2 (0.38) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL8417160 | 0.84 | MAPK1 (0.46) | CES2CES1TSHRALDH1A1MAPT | |
| SCHEMBL8415509 | 0.84 | MAPK1 (0.46) | CES2CES1TSHRALDH1A1MAPT | |
| SCHEMBL8415644 | 0.84 | MAPK1 (0.46) | CES2CES1TSHRALDH1A1MAPT | |
| SCHEMBL11176163 | 0.82 | KDM4C (0.42) | CHRNB2CHRNB4CHRNA4MAPTMAPK1 | |
| SCHEMBL5140309 | 0.81 | TSHR (0.32) | FFAR3TSHRALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL2035630 | 0.78 | CES2 (0.41) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL28639265 | 0.76 | CES2 (0.39) | CES2CES1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021345-A1 | HYDROXYLATED AMIDE SKIN MOISTURIZER | L'Oreal (FR) | 2009-02-11 | — | — | EP | claimed |
| WO-2007137925-A1 | HYDROXYLATED AMIDE SKIN MOISTURIZER | L'OREAL (FR) | 2007-12-06 | — | — | WO | claimed |
| US-8361991-B2 | Hydroxylated amide skin moisturizer | L'OREAL (FR) | 2013-01-29 | — | — | US | disclosed |
| US-20100009933-A1 | HYDROXYLATED AMIDE SKIN MOISTURIZER | L'OREAL (FR) | 2010-01-14 | — | — | US | disclosed |
| EP-2021345-A1 | HYDROXYLATED AMIDE SKIN MOISTURIZER | L'Oreal (FR) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007137925-A1 | HYDROXYLATED AMIDE SKIN MOISTURIZER | L'OREAL (FR) | 2007-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009933-A1 | HYDROXYLATED AMIDE SKIN MOISTURIZER | H1-0, H1-3, H1-4 | CES2 1568/4885CES1 977/4885HDAC3 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.