Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261266 | 0.89 | GAA (0.60) | MAPTNPC1RAB9AMITFKMT2A | |
| SCHEMBL3265584 | 0.84 | NPC1 (0.51) | MAPTNPC1RAB9AMITFKMT2A | |
| SCHEMBL7753154 | 0.73 | TSHR (0.53) | MAPTNPC1RAB9AMITFKMT2A | |
| SCHEMBL4775831 | 0.73 | KMT2A (0.51) | MAPTNPC1RAB9AKMT2ALMNA | |
| SCHEMBL11050609 | 0.70 | GAA (0.53) | MAPTNPC1RAB9AMITFKMT2A | |
| SCHEMBL7656234 | 0.69 | ALDH1A1 (0.53) | MAPTNPC1RAB9AKMT2ALMNA | |
| SCHEMBL3259617 | 0.68 | DHFR (0.51) | MAPTKMT2ALMNAGAAALOX15 | |
| SCHEMBL11003374 | 0.68 | TSHR (0.47) | MAPTNPC1RAB9AMITFKMT2A | |
| SCHEMBL14879550 | 0.67 | TSHR (0.46) | MAPTNPC1RAB9AMITFKMT2A | |
| SCHEMBL23399618 | 0.66 | GAA (1.00) | MAPTNPC1RAB9AKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |